Catalyst and solvent-free cyclopropanation of electron-deficient olefins with cyclic diazoamides for the synthesis of spiro[cyclopropane-1,3′-indolin]-2′-one derivatives

被引：27

作者：

Karthik, Govindaraju ^{[1
]}

Rajasekaran, Tamilselvan ^{[1
]}

Sridhar, B. ^{[2
]}

Reddy, B. V. Subba ^{[1
]}

机构：

[1] CSIR, Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

[2] CSIR, Indian Inst Chem Technol, Lab Xray Crystallog, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 51期

关键词：

Diazoamide; Catalyst-free cyclopropanation; Spirooxindole; Spirocyclopropane; REVERSE-TRANSCRIPTASE INHIBITORS; DONOR-ACCEPTOR CYCLOPROPANES; DIASTEREOSELECTIVE SYNTHESIS; BIOLOGICAL EVALUATIONS; 3-COMPONENT REACTION; DESIGN; CYCLOADDITIONS; ALDEHYDES; FACILE; OXINDOLES;

D O I：

10.1016/j.tetlet.2014.10.137

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel series of spirooxindolylcyclopropane derivatives have been synthesized in high yields from 3-diazooxindole and electron deficient olefins under catalyst/solvent-free conditions. (C) 2014 Published by Elsevier Ltd.

引用

页码：7064 / 7067

页数：4

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