Electrophysiological Substrate for a Dominant Reentrant Source During Atrial Fibrillation

被引：8
|
作者：
Aslanidi, Oleg V. [1 ]
Robinson, Robert [1 ]
Cheverton, Deborah [1 ]
Boyett, Mark R. [2 ]
Zhang, Henggui [1 ]
机构：
[1] Univ Manchester, Sch Phys & Astron, Manchester M13 9PL, Lancs, England
[2] Univ Manchester, Fac Med & Human Sci, Manchester M13 9NT, Lancs, England
来源：
2009 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-20 | 2009年
基金：
英国生物技术与生命科学研究理事会;
关键词：
TRANSIENT OUTWARD CURRENT; REGIONAL DIFFERENCES; IONIC MECHANISMS; CANINE RIGHT; REPOLARIZATION; MODEL; INHOMOGENEITIES; HETEROGENEITY; CONDUCTION; LESIONS;
D O I：
10.1109/IEMBS.2009.5333573
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Experimentally observed differences in the action potential (AP) properties between the left (LA) and right (RA) atria are believed to be important in maintaining reentrant sources during atrial fibrillation. We incorporate AP models for single LA and RA cells, as well as major intra- and interatrial conduction pathways, into a 2D atrial tissue model and study the role of tissue heterogeneity in global interactions between reentrant spiral waves in both atria. Our simulations show that shorter AP refractoriness in the LA translates into a shorter period of spiral rotation, and as a result, reentry in the LA dominates the overall excitation patterns in the atria.
引用
收藏
页码：2819 / 2822
页数：4
相关论文
共 50 条
  • [1] Left to Right Atrial Electrophysiological Differences: Substrate for a Dominant Reentrant Source during Atrial Fibrillation
    Aslanidi, Oleg V.
    Boyett, Mark R.
    Zhang, Henggui
    FUNCTIONAL IMAGING AND MODELING OF THE HEART, PROCEEDINGS, 2009, 5528 : 154 - 161
  • [2] Idiopathic atrial fibrillation: Which electrophysiological substrate?
    Hauer, R. N. W.
    Cardiac Arrhythmias 2005, 2005, : 57 - 60
  • [3] Assisting Electrophysiological Substrate Quantification in Atrial Fibrillation Ablation
    Vraka, Aikaterini
    Hornero, Fernando
    Osca, Joaquin
    Faes, Luca
    Alcaraz, Ratil
    Rieta, Jose J.
    2019 E-HEALTH AND BIOENGINEERING CONFERENCE (EHB), 2019,
  • [4] Electrophysiological Predictors of Susceptible Atrial Substrate for the Onset and Recurrence of Atrial Fibrillation
    Mayer, Michael
    Aziz, Zaid
    Deshmukh, Amrish
    Al Kassem, Hatem
    Beaser, Andrew
    Upadhyay, Gaurav A.
    Emami, Maryam
    Ozcan, Cevher
    CIRCULATION, 2023, 148
  • [5] Electrophysiological predictors of susceptible atrial substrate for the onset and recurrence of atrial fibrillation
    Ozcan, Cevher
    Aziz, Zaid
    Mayer, Michael
    Deshmukh, Amrish
    Al Kassem, Hatem
    Upadhyay, Gaurav
    Beaser, Andrew
    Emami, Maryam
    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 2024,
  • [6] Atrioventricular nodal reentrant tachycardia with paroxysmal atrial fibrillation: Clinical and electrophysiological features and predictors of atrial fibrillation recurrence following elimination of atrioventricular nodal reentrant tachycardia
    Amasyali, B
    Kose, S
    Aytemir, K
    Kilic, A
    Heper, G
    Kursaklioglu, H
    Iyisoy, A
    Celik, T
    Kaya, EB
    Isik, E
    JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 2005, 13 (03) : 195 - 201
  • [7] Atrioventricular Nodal Reentrant Tachycardia with Paroxysmal Atrial Fibrillation: Clinical and Electrophysiological Features and Predictors of Atrial Fibrillation Recurrence Following Elimination of Atrioventricular Nodal Reentrant Tachycardia
    Basri Amasyali
    Sedat Kose
    Kudret Aytemir
    Ayhan Kilic
    Gulumser Heper
    Hurkan Kursaklioglu
    Atila Iyisoy
    Turgay Celik
    E. Bariş Kaya
    Ersoy Isik
    Journal of Interventional Cardiac Electrophysiology, 2005, 13 : 195 - 201
  • [8] A single pulmonary vein as electrophysiological substrate of paroxysmal atrial fibrillation
    Huang, He
    Wang, Xingxiang
    Chun, Julian
    Ernst, Sabine
    Satomi, Kazuhiro
    Ujeyl, Amaar
    Chu, Huimin
    Shi, Haifeng
    Baensch, Dietmar
    Antz, Matthias
    Kuck, Karl-Heinz
    Ouyang, Feifan
    JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2006, 17 (11) : 1193 - 1201
  • [9] Dominant frequency during atrial fibrillation correlates poorly with atrial fibrillation cyclelength
    Van Bemmel, M. W.
    Elvan, A.
    Linnenbank, A. C.
    Misier, A. R. Ramdat
    Delnoy, P. P. H. M.
    Beukema, W. P.
    Sie, H. T.
    De Bakker, J. M. T.
    EUROPEAN HEART JOURNAL, 2007, 28 : 643 - 643
  • [10] Efficacy of atrial substrate modification based on dominant frequency of paroxysmal atrial fibrillation
    Kumagai, Koji
    Minami, Kentaro
    Kutsuzawa, Daisuke
    Oshima, Shigeru
    JOURNAL OF ARRHYTHMIA, 2016, 32 (03) : 212 - 217
12345