Management of Splanchnic Vein Thrombosis in Patients With Acute Pancreatitis An International Survey of Current Practice

被引:5
作者
Ghazanfar, Mudassar A. [1 ]
Ke, Lu [2 ]
Ramsay, George [3 ]
Smith, Martin [4 ]
Giovinazzo, Francesco [5 ]
Mohamed, Moustafa [6 ]
Pandanaboyana, Sanjay [7 ]
Huang, Wei [8 ]
Ahmed, Irfan [1 ]
Siriwardena, Ajith K. [9 ]
Windsor, John A. [10 ]
Bekheit, Mohamed [11 ,12 ]
机构
[1] Aberdeen Royal Infirm, Dept Surg, HPB Surg Unit, NHS Grampian, Aberdeen, Scotland
[2] Nanjing Univ, Jinling Hosp, Surg Crit Care, Nanjing, Peoples R China
[3] Aberdeen Royal Infirm, Dept Surg, Colorectal Surg Unit, NHS Grampian, Aberdeen, Scotland
[4] WITS Univ Hosp, Dept Surg, Johannesburg, South Africa
[5] Policlin Gemelli, Dept Surg, Rome, Italy
[6] Klinikum Oldenburg, Dept Gastroenterol & Intervent Endoscopy, Oldenburg, Germany
[7] Freeman Rd Hosp, Dept HPB & Liver Transplant Surg, Newcastle Upon Tyne, England
[8] Sichuan Univ, West China Hosp, Chengdu, Peoples R China
[9] Manchester Royal Infirm, HPB Surg Unit, Manchester, England
[10] Auckland Univ Hosp, Dept Gen Surg, Upper GI Unit, HBP, Auckland, New Zealand
[11] Elite Hosp, Dr Grays Hosp, Scotland Integrated Ctr HPB Care, Dept Surg,NHS Grampian, Alexandria, Egypt
[12] Elite Hosp, Surg Div, Hepat, 1 Villas St,Ring Rd, Alexandria, Egypt
关键词
acute pancreatitis; anticoagulation; splanchnic circulation; thrombosis; VENOUS THROMBOSIS; COMPLICATIONS;
D O I
10.1097/MPA.0000000000002165
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
ObjectivesSplanchnic venous thrombosis (SpVT) is a complication of acute pancreatitis (AP). There is scarce literature on the prevalence and treatment of SpVT in AP. The aim of this international survey was to document current approaches to the management of SpVT in patients with AP.MethodsAn online survey was designed by a group of international experts in the management of AP. Twenty-eight questions covered the level of experience of the respondents, disease demographics, and management of SpVT.ResultsThere were 224 respondents from 25 countries. Most respondents (92.4%, n = 207) were from tertiary hospitals and predominantly consultants (attendings, 86.6%, n = 194). More than half of the respondents (57.2%, n = 106) "routinely" prescribed prophylactic anticoagulation for AP. Less than half of the respondents (44.3%, n = 82) "routinely" prescribed therapeutic anticoagulation for SpVT. A clinical trial was considered justified by most respondents (85.4%, n = 157) and 73.2% (n = 134) would be willing to enroll their patients.ConclusionsThe approach to anticoagulation in the treatment of patients with SpVT complicating AP was highly variable. Respondents indicate that a position of equipoise exists to justify randomized evaluation.
引用
收藏
页码:1211 / 1216
页数:6
相关论文
共 24 条
[1]   Role of thrombophilia in splanchnic venous thrombosis in acute pancreatitis [J].
Ahmed, Sobur Uddin ;
Rana, Surinder S. ;
Ahluwalia, Jasmina ;
Varma, Neelam ;
Sharma, Ravi ;
Gupta, Rajesh ;
Kang, Mandeep .
ANNALS OF GASTROENTEROLOGY, 2018, 31 (03) :371-378
[2]  
Aswani Y, 2015, J PANCREAS, V16, P20, DOI 10.6092/1590-8577/2889
[3]   Hemorrhagic complications of pancreatitis: Radiologic evaluation with emphasis on CT imaging [J].
Balthazar, EJ ;
Fisher, LA .
PANCREATOLOGY, 2001, 1 (04) :306-313
[4]   Splanchnic vein thrombosis complicating severe acute pancreatitis [J].
Besselink, Marc G. H. .
HPB, 2011, 13 (12) :831-832
[5]   Natural history of pancreatitis-induced splenic vein thrombosis: a systematic review and meta-analysis of its incidence and rate of gastrointestinal bleeding [J].
Butler, James R. ;
Eckert, George J. ;
Zyromski, Nicholas J. ;
Leonardi, Michael J. ;
Lillemoe, Keith D. ;
Howard, Thomas J. .
HPB, 2011, 13 (12) :839-845
[6]   Influence of portal vein occlusion on portal flow and liver elasticity in an animal model [J].
Chatelin, Simon ;
Pop, Raoul ;
Giraudeau, Celine ;
Ambarki, Khalid ;
Jin, Ning ;
Severac, Francois ;
Breton, Elodie ;
Vappou, Jonathan .
NMR IN BIOMEDICINE, 2021, 34 (06)
[7]   Early Spontaneous Abdominal Bleeding is associated with Poor Outcome in Moderate to Severe Acute Pancreatitis Patients: A Propensity Matched Study [J].
Chen, Yizhe ;
Zhou, Jing ;
Li, Gang ;
Tong, Zhihui ;
Dong, Jie ;
Pan, Yiyuan ;
Ke, Lu ;
Li, Weiqin ;
Li, Jieshou .
SCIENTIFIC REPORTS, 2017, 7
[8]   Splanchnic vein thrombosis in severe acute pancreatitis: a 2-year, single-institution experience [J].
Gonzelez, Hector Jazmin ;
Sahay, Samir J. ;
Samadi, Benny ;
Davidson, Brian Ritchie ;
Rahman, Sakhawat Hussain .
HPB, 2011, 13 (12) :860-864
[9]  
Gotto Antonio, 2014, BMJ Case Rep, V2014, DOI 10.1136/bcr-2013-201359
[10]   Challenge to the Intestinal Mucosa During Sepsis [J].
Haussner, Felix ;
Chakraborty, Shinjini ;
Halbgebauer, Rebecca ;
Huber-Lang, Markus .
FRONTIERS IN IMMUNOLOGY, 2019, 10