A Retrospective Analysis of Female Mullerian Duct Anomalies in Association With Congenital Renal Abnormalities

被引:10
作者
Mooren, Eline R. M. [1 ]
Cleypool, Cindy G. J. [2 ]
de Kort, Laetitia M. O. [1 ]
Goverde, Angelique J. [3 ]
Dik, Pieter [1 ,4 ]
机构
[1] UMC Utrecht, Wilhelmina Childrens Hosp, Dept Pediat Urol, POB 85090, NL-3508 AB Utrecht, Netherlands
[2] Univ Utrecht, Univ Med Ctr Utrecht, Dept Anat, Div Surg Specialt, Utrecht, Netherlands
[3] Univ Med Ctr Utrecht, Dept Reprod Med & Gynaecol, Utrecht, Netherlands
[4] IM Sechenov First Moscow State Med Univ, Dept Pediat Surg, Div Pediat Urol & Androl, Moscow, Russia
关键词
Mullerian ducts; Urogenital system; Urogenital abnormalities; GENITAL-TRACT; UTERINE ANOMALIES; KIDNEY; WOMEN; MALFORMATIONS; PREVALENCE; HEMIVAGINA; DIAGNOSIS; AGENESIS; CHILDREN;
D O I
10.1016/j.jpag.2021.04.013
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Study objective: Mullerian (paramesonephric) duct anomalies (MDAs) are associated with several coexisting congenital abnormalities, in-cluding renal abnormalities. Although congenital renal abnormalities may remain asymptomatic, the consequences should not be underes-timated. In both the literature and clinical practice, it remains necessary to improve awareness of the co-occurrence of different congenital renal abnormalities in women with MDAs. To gain further insight into this co-occurrence and to estimate whether guidelines for women with MDAs should be optimized, this study was performed. Design: A descriptive retrospective analysis. Setting: University Medical Centre Utrecht in the Netherlands. Participants: Women with MDAs diagnosed or treated between 1980 and 2015. Interventions: None. Main outcome measures: The prevalence of the co-occurrence of congenital renal abnormalities in women with MDAs. Results: Renal status was recorded in 186 of 255 women (72.9%), and the other women (27.1%) did not have a retrievable renal status. Congenital renal abnormalities were present in 90 of 186 women (48.4%) and were observed most frequently in women having a duplex uterus with obstructed hemivagina. The most common renal abnormality was unilateral renal agenesis, which was observed in 58 of 90 women (64.4%). Conclusions: MDAs are highly associated with different congenital renal abnormalities, and these results emphasize that women with MDAs should be routinely screened for their co-occurrence. However, these results also highlight that there remains a lack of awareness of this association. Whether all women with congenital renal abnormalities should be routinely screened for MDAs requires further investigation.
引用
收藏
页码:681 / 685
页数:5
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