A simple mathematical model for relapsing-remitting multiple sclerosis (RRMS)

被引：10
作者：
Elettreby, M. F. [1 ,2 ]
Ahmed, E. [2 ]
机构：
[1] King Khalid Univ, Fac Sci, Math Dept, Abha 9004, Saudi Arabia
[2] Mansoura Univ, Fac Sci, Math Dept, Mansoura 35516, Egypt
来源：
MEDICAL HYPOTHESES | 2020年 / 135卷
关键词：
Multiple sclerosis; Relapse; Recurrence; Autoimmune diseases; Complex system; MATTER VOLUME; LYMPHOCYTES; CYTOKINES; BRAIN; GREY;
D O I：
10.1016/j.mehy.2019.109478
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Multiple sclerosis is one of the most common autoimmune-related neurological disorders affecting the central nervous system. One of its main properties is dissemination of lesions in time and space. Here, we propose a simple mathematical model to describe the stages of disease progression with recurrence. We tried to find the steady states and evaluated their stability to identify the necessary conditions to produce the recurrence. Also, we described the analytical results with some numerical simulations.
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页数：5
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