Ligand exchange and MIP-based paraoxon memories onto QCM sensor

被引：6
作者：
Ozkutuk, Ebru Birlik [1 ]
Diltemiz, Sibel Emir [2 ]
Ozalp, Elif [1 ]
Uzun, Lokman [3 ]
Ersoz, Arzu [2 ]
机构：
[1] Eskisehir Osmangazi Univ, Dept Chem, Eskisehir, Turkey
[2] Anadolu Univ, Dept Chem, Eskisehir, Turkey
[3] Hacettepe Univ, Dept Chem, TR-06532 Ankara, Turkey
来源：
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING | 2015年 / 119卷 / 01期
关键词：
MOLECULARLY IMPRINTED POLYMERS; QUARTZ-CRYSTAL MICROBALANCE; RECOGNITION SITES; SEPARATION; ANTIBODY; SYSTEM;
D O I：
10.1007/s00339-014-8974-2
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
In this study, we have aimed to prepare quartz crystal microbalance (QCM) sensor using paraoxon-imprinted particles. Firstly, methacryloyl antipyrine (MAAP)-based metal-chelate-coordinated pre-complex has been prepared and used for paraoxon templation. Then, paraoxon-imprinted nanofilms were formed on QCM sensor after modification of the gold surfaces with allyl mercaptan. By this way, specific and selective memories, which depend on metal-chelate interactions between Eu(III) ions and template, for paraoxon molecules have been obtained on the electrode surface. QCM sensor has characterized using AFM and ellipsometer. The detection limit and the affinity constant have found to be 0.09 mu M and 5.71 x 10(3) M-1 for MAAP-Eu paraoxon-based nanofilm, respectively. The specificity of the QCM sensor has shown using parathion as a competitor molecule.
引用
收藏
页码：351 / 357
页数：7
相关论文
共 38 条
  • [1] Molecularly imprinted polymers for drug delivery
    Alvarez-Lorenzo, C
    Concheiro, A
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2004, 804 (01): : 231 - 245
  • [2] Molecular imprinting based composite cryogel membranes for purification of anti-hepatitis B surface antibody by fast protein liquid chromatography
    Asliyuce, Sevgi
    Uzun, Lokman
    Rad, Abbas Yousefi
    Unal, Serhat
    Say, Ridvan
    Denizli, Adil
    [J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2012, 889 : 95 - 102
  • [3] Preparation and evaluation of molecularly imprinted polymer liquid chromatography column for the separation of Cathine enantiomers
    Balamurugan, Krishnamoorthy
    Gokulakrishnan, Kannan
    Prakasam, Tangirala
    [J]. SAUDI PHARMACEUTICAL JOURNAL, 2012, 20 (01) : 53 - 61
  • [4] Preconcentration of copper using double-imprinted polymer via solid phase extraction
    Birlik, E
    Ersöz, A
    Denizli, A
    Say, R
    [J]. ANALYTICA CHIMICA ACTA, 2006, 565 (02) : 145 - 151
  • [5] Chambers H.W., 1992, ORGANOPHSOPHATES, P3
  • [6] Fluorescence-based optical sensor design for molecularly imprinted polymers
    Chen, YC
    Brazier, JJ
    Yan, MD
    Bargo, PR
    Prahl, SA
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2004, 102 (01): : 107 - 116
  • [7] Molecularly imprinted ligand-exchange recognition assay of DNA by SPR system using guanosine and guanine recognition sites of DNA
    Diltemiz, S. Emir
    Denizli, Adil
    Ersoez, Arzu
    Say, Ridvan
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2008, 133 (02) : 484 - 488
  • [8] Designing of MIP based QCM sensor having thymine recognition sites based on biomimicking DNA approach
    Diltemiz, S. Emir
    Hur, D.
    Ersoz, A.
    Denizli, A.
    Say, R.
    [J]. BIOSENSORS & BIOELECTRONICS, 2009, 25 (03) : 599 - 603
  • [9] 8-OHdG sensing with MIP based solid phase extraction and QCM technique
    Ersoez, Arzu
    Diltemiz, S. Emir
    Oezcan, A. Atilir
    Denizli, Adil
    Say, Ridvan
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2009, 137 (01): : 7 - 11
  • [10] Removal of phenolic compounds with nitrophenol-imprinted polymer based on π-π and hydrogen-bonding interactions
    Ersöz, A
    Denizli, A
    Sener, I
    Atilir, A
    Diltemiz, S
    Say, R
    [J]. SEPARATION AND PURIFICATION TECHNOLOGY, 2004, 38 (02) : 173 - 179
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