Convenient preparation of aryl ether derivatives using a sequence of functionalized polymers

被引:12
|
作者
Lizarzaburu, ME [1 ]
Shuttleworth, SJ [1 ]
机构
[1] Tularik Inc, San Francisco, CA 94080 USA
关键词
D O I
10.1016/S0040-4039(03)01117-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A four-step synthesis to aryl ether derivatives, three of which utilize polymer-supported reagents, has been developed. Supported triphenylphosphine was successfully utilized in two distinct synthetic processes in the first step, whilst supported base and ionic and covalent scavengers were employed to complete the synthesis and purification of the target compounds. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:4873 / 4876
页数:4
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