Socioeconomic Factors Associated With Glycemic Measurement and Poor HbA1c Control in People With Type 2 Diabetes: The Global DISCOVER Study

被引:20
作者
Gomes, Marilia B.
Tang, Fengming
Chen, Hungta
Cid-Ruzafa, Javier
Fenici, Peter
Khunti, Kamlesh
Rathmann, Wolfgang
Shestakova, Marina V.
Surmont, Filip
Watada, Hirotaka
Medina, Jesus
Shimomura, Iichiro
Saraiva, Gabriela Luporini
Cooper, Andrew
Nicolucci, Antonio
机构
[1] Department of Medicine, Diabetes Unit, Rio de Janeiro State University, Rio de Janeiro
[2] Saint Luke’s Mid America Heart Institute, Kansas City, MO
[3] Medical/Payer Evidence Statistics, BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, MD
[4] Barcelona, Evidera
[5] BioPharmaceuticals Medical, AstraZeneca, Cambridge
[6] Primary Care Diabetes and Vascular Medicine, University of Leicester, Leicester
[7] Institute for Biometrics and Epidemiology, German Diabetes Centre, Düsseldorf
[8] Endocrinology Research Centre, Diabetes Institute, Moscow
[9] BioPharmaceuticals Medical, AstraZeneca, Luton
[10] Graduate School of Medicine, Juntendo University, Tokyo
[11] BioPharmaceuticals Medical, AstraZeneca, Madrid
[12] Graduate School of Medicine, Osaka University, Osaka
[13] Centre for Outcomes Research and Clinical Epidemiology, Pescara
来源
FRONTIERS IN ENDOCRINOLOGY | 2022年 / 13卷
基金
日本科学技术振兴机构;
关键词
type; 2; diabetes; observational study; socioeconomic factors; glycemic control; glucose-lowering drug; HEALTH; COMPLICATIONS; DETERMINANTS; RATIONALE; POSITION; OUTCOMES; ADULTS; CARE;
D O I
10.3389/fendo.2022.831676
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
DISCOVER is a 3-year observational study program of 15,983 people with type 2 diabetes initiating second-line glucose-lowering therapy in 38 countries. We investigated the association between socioeconomic status and both the availability of a baseline glycated hemoglobin (HbA1c) measurement and poor glycemic control (HbA1c level >= 9.0%) in participants enrolled in DISCOVER. Factors associated with a lack of baseline HbA1c measurement or an HbA1c level >= 9.0% were assessed using three-level hierarchical logistic models. Overall, 19.1% of participants did not have a baseline HbA1c measurement recorded. Lower-middle country income (vs. high) and primary/no formal education (vs. university education) were independently associated with a reduced likelihood of having a baseline HbA1c measurement (odds ratio [95% confidence interval]: 0.11 [0.03-0.49] and 0.81 [0.66-0.98], respectively. Of the participants with an available HbA1c measurement, 26.9% had an HbA1c level >= 9.0%; 68.7% of these individuals were from lower- or upper-middle-income countries. Factors associated with an increased likelihood of poor glycemic control included low country income, treatment at a site with public and/or governmental funding (vs. private funding) and having public or no health insurance (vs. private). A substantial proportion of DISCOVER participants did not have an HbA1c measurement; more than one-quarter of these participants had poorly controlled type 2 diabetes. Both individual- and country-level socioeconomic factors are associated with the quality of care regarding glycemic control. Awareness of these factors could help improve the management of patients with type 2 diabetes.
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页数:9
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