Dynamics and clustering of IRE1α during ER stress

被引：10
|
作者：
Rainbolt, T. Kelly [1 ]
Frydman, Judith [1 ,2 ]
机构：
[1] Stanford Univ, Dept Biol, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Genet, Stanford, CA 94305 USA
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2020年 / 117卷 / 07期
关键词：
UNFOLDED PROTEIN RESPONSE; IRE1; ACTIVATION; REVEALS; SIGNALS; FATE;
D O I：
10.1073/pnas.1921799117
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：3352 / 3354
页数：3
相关论文
共 50 条
  • [31] Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling
    Cohen, Nir
    Breker, Michal
    Bakunts, Anush
    Pesek, Kristina
    Chas, Ainara
    Argemi, Josepmaria
    Orsi, Andrea
    Gal, Lihi
    Chuartzman, Silvia
    Wigelman, Yoav
    Jonas, Felix
    Walter, Peter
    Ernst, Robert
    Aragon, Tomas
    van Anken, Eelco
    Schuldiner, Maya
    JOURNAL OF CELL SCIENCE, 2017, 130 (19) : 3222 - +
  • [32] Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress
    Tay, Kwang Hong
    Luan, Qi
    Croft, Amanda
    Jiang, Chen Chen
    Jin, Lei
    Zhang, Xu Dong
    Tseng, Hsin-Yi
    CELLULAR SIGNALLING, 2014, 26 (02) : 287 - 294
  • [33] Chaperone BiP controls ER stress sensor Ire1 through interactions with its oligomers
    Dawes, Sam
    Hurst, Nicholas
    Grey, Gabriel
    Wieteska, Lukasz
    Wright, Nathan, V
    Manfield, Iain W.
    Hussain, Mohammed H.
    Kalverda, Arnout P.
    Lewandowski, Jozef R.
    Chen, Beining
    Zhuravleva, Anastasia
    LIFE SCIENCE ALLIANCE, 2024, 7 (10)
  • [34] Mammalian IRE1α dynamically and functionally coalesces with stress granules
    Liu, Songzi
    Zhang, Xiaoge
    Yao, Xin
    Wang, Guan
    Huang, Shijia
    Chen, Peng
    Tang, Mingliang
    Cai, Jie
    Wu, Zhuyin
    Zhang, Yiliang
    Xu, Rongzhi
    Liu, Kai
    He, Kangmin
    Wang, Yan
    Jiang, Lei
    Wang, Qiong A.
    Rui, Liangyou
    Liu, Jianmiao
    Liu, Yong
    NATURE CELL BIOLOGY, 2024, 26 (06) : 917 - 931
  • [35] Fission yeast Bsd1 is required for ER stress response in Ire1 independent manner
    Mahapatra, Pinaki Prasad
    Ahmed, Shakil
    MOLECULAR BIOLOGY REPORTS, 2025, 52 (01)
  • [36] UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor
    Kopp, Megan C.
    Larburu, Natacha
    Durairaj, Vinoth
    Adams, Christopher J.
    Ali, Maruf M. U.
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2019, 26 (11) : 1053 - +
  • [37] Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1
    Oikawa, Daisuke
    Kimata, Yukio
    Kohno, Kenji
    JOURNAL OF CELL SCIENCE, 2007, 120 (09) : 1681 - 1688
  • [38] AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts
    Sanchez-Alvarez, Miguel
    Angel del Pozo, Miguel
    Bakal, Chris
    SCIENTIFIC REPORTS, 2017, 7
  • [39] Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death
    Pinkaew, Decha
    Chattopadhyay, Abhijnan
    King, Matthew D.
    Chunhacha, Preedakorn
    Liu, Zhihe
    Stevenson, Heather L.
    Chen, Yanjie
    Sinthujaroen, Patuma
    McDougal, Owen M.
    Fujise, Ken
    NATURE COMMUNICATIONS, 2017, 8
  • [40] Microglial ER stress response via IRE1α regulates diet-induced metabolic imbalance and obesity in mice
    Stilgenbauer, L.
    Chen, Q.
    Pungi, D.
    James, N.
    Jayarathne, H.
    Koshko, L.
    Scofield, S.
    Zhang, K.
    Sadagurski, M.
    MOLECULAR METABOLISM, 2025, 95
12345