Dynamics and clustering of IRE1α during ER stress

被引:10
|
作者
Rainbolt, T. Kelly [1 ]
Frydman, Judith [1 ,2 ]
机构
[1] Stanford Univ, Dept Biol, Stanford, CA 94305 USA
[2] Stanford Univ, Dept Genet, Stanford, CA 94305 USA
关键词
UNFOLDED PROTEIN RESPONSE; IRE1; ACTIVATION; REVEALS; SIGNALS; FATE;
D O I
10.1073/pnas.1921799117
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:3352 / 3354
页数:3
相关论文
共 50 条
  • [21] Emerging roles for the ER stress sensor IRE1? in metabolic regulation and disease
    Huang, Shijia
    Xing, Yuying
    Liu, Yong
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 294 (49) : 18726 - 18741
  • [22] BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE1α
    Lisbona, Fernanda
    Rojas-Rivera, Diego
    Thielen, Peter
    Zamorano, Sebastian
    Todd, Derrick
    Martinon, Fabio
    Glavic, Alvaro
    Kress, Christina
    Lin, Jonathan H.
    Walter, Peter
    Reed, John C.
    Glimcher, Laurie H.
    Hetz, Claudio
    MOLECULAR CELL, 2009, 33 (06) : 679 - 691
  • [23] MMP-2 inhibition attenuates ER stress-mediated cell death during myocardial ischemia-reperfusion injury by preserving IRE1α
    Bassiouni, Wesam
    Mahmud, Zabed
    Simmen, Thomas
    Seubert, John M.
    Schulz, Richard
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2025, 198 : 74 - 88
  • [24] Binding of human BiP to the ER stress transducers IRE1 and PERK requires ATP
    Sou, Si Nga
    Ilieva, Kristina M.
    Polizzi, Karen M.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 420 (02) : 473 - 478
  • [25] Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
    Le Thomas, Adrien
    Ferri, Elena
    Marsters, Scot
    Harnoss, Jonathan M.
    Lawrence, David A.
    Zuazo-Gaztelu, Iratxe
    Modrusan, Zora
    Chan, Sara
    Solon, Margaret
    Chalouni, Cecile
    Li, Weihan
    Koeppen, Hartmut
    Rudolph, Joachim
    Wang, Weiru
    Wu, Thomas D.
    Walter, Peter
    Ashkenazi, Avi
    NATURE COMMUNICATIONS, 2021, 12 (01)
  • [26] Multiple roles of the ER stress sensor IRE1 demonstrated by gene targeting in rice
    Wakasa, Yuhya
    Hayashi, Shimpei
    Ozawa, Kenjirou
    Takaiwa, Fumio
    SCIENTIFIC REPORTS, 2012, 2
  • [27] Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
    Shemorry, Anna
    Harnoss, Jonathan M.
    Guttman, Ofer
    Marsters, Scot A.
    Komuves, Liszlo G.
    Lawrence, David A.
    Ashkenazi, Avi
    ELIFE, 2019, 8
  • [28] Study on the effect of IRE1α on cell growth and apoptosis via modulation PLK1 in ER stress response
    Li, Xiangzhu
    Zhu, Huifang
    Huang, Huizhe
    Jiang, Rong
    Zhao, Wenjun
    Liu, Yanna
    Zhou, Jinghua
    Guo, Feng-Jin
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2012, 365 (1-2) : 99 - 108
  • [29] EI24 promotes cell adaption to ER stress by coordinating IRE1 signaling and calcium homeostasis
    Xu, Yiwei
    Chen, Jie
    Chen, Jianguo
    Teng, Junlin
    EMBO REPORTS, 2022, 23 (03)
  • [30] ER stress signaling by regulated splicing:: IRE1/HAC1/XBP1
    Back, SH
    Schröder, M
    Lee, K
    Zhang, KZ
    Kaufman, RJ
    METHODS, 2005, 35 (04) : 395 - 416