Update of Chlamydia trachomatis infection

被引：3
作者：
Debonnet, C. [1 ]
Robin, G. [1 ,2 ]
Prasivoravong, J. [2 ]
Vuotto, F. [3 ]
Catteau-Jonard, S. [1 ]
Faure, K. [3 ]
Dessein, R. [4 ]
Robin, C. [1 ]
机构：
[1] Univ Lille, Serv Med Reprod, CHU Lille, F-59000 Lille, France
[2] Univ Lille, Serv Androl, CHU Lille, F-59000 Lille, France
[3] Univ Lille, Serv Malad Infect, CHU Lille, F-59000 Lille, France
[4] Univ Lille, Inst Microbiol & Serv Bacteriol, CHU Lille, F-59000 Lille, France
来源：
GYNECOLOGIE OBSTETRIQUE FERTILITE & SENOLOGIE | 2021年 / 49卷 / 7-8期
关键词：
Chlamydia trachomatis; Infertility; Urogenital microbiota; ART; Genital tract infection; PELVIC-INFLAMMATORY-DISEASE; TUBAL FACTOR SUBFERTILITY; NEISSERIA-GONORRHOEAE; MOLECULAR-MECHANISMS; COST-EFFECTIVENESS; INFERTILE WOMEN; NATURAL COURSE; GENITAL-TRACT; ANTIBODY; PATHOGENESIS;
D O I：
10.1016/j.gofs.2021.01.003
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Chlamydia trachomatis (CT) is the most common sexually transmitted bacterial infection worldwide. It is asymptomatic in most cases and mainly affects young women, with potential long term sequelae (pelvic inflammatory disease, tubal infertility, obstetric complications). The impact on male fertility is controversial. Screening methods as well as antibiotics use have recently been reassessed due to resistance phenomena and the negative effect on the urogenital microbiota. Positive CT serology may be indicative of tuboperitoneal pathology, which may not be noticed on hysterosalpingography. New research on single-nucleotide polymorphisms (SNPs) aims to establish a patient profile at higher risk of infectious tubal damage due to CT. CT seropositivity is also associated with decreased spontaneous pregnancy rates and is a predictive factor for obstetrical complications. (C) 2021 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：608 / 616
页数：9
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