Ruthenium-catalyzed Decarboxylative and Dehydrogenative Formation of Highly Substituted Pyridines from Alkene-tethered Isoxazol-5(4H)-ones

被引：21

作者：

Okamoto, Kazuhiro ^{[1
]}

Sasakura, Kohei ^{[1
]}

Shimbayashi, Takuya ^{[1
]}

Ohe, Kouichi ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Energy & Hydrocarbon Chem, Nishikyo Ku, Kyoto 6158510, Japan

来源：

CHEMISTRY LETTERS | 2016年 / 45卷 / 08期

关键词：

Multisubstituted pyridine; Ruthenium catalyst; Isoxazolone; REDUCTIVE N-HETEROCYCLIZATION; VINYL AZIDES; SELECTIVE SYNTHESIS; ALKYNES SYNTHESIS; PALLADIUM; DERIVATIVES; OXIMES; CYCLIZATION; KETOXIMES; FUNCTIONALIZATION;

D O I：

10.1246/cl.160480

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A ruthenium-catalyzed reaction of alkene-tethered isoxazol-5(4H)-ones affording pyridines has been developed. Di-, tri-, and tetrasubstituted pyridines were obtained from various isoxazolones in good yields.

引用

页码：988 / 990

页数：3

共 54 条

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