Synthesis of Spiro[indoline-3,4′-pyrano[3,2-c]chromene]diones

被引:6
|
作者
Ghadiri, Sakineh [1 ]
Bayat, Mohammad [1 ]
Hosseini, Fahimeh Sadat [1 ]
机构
[1] Imam Khomeini Int Univ, Dept Chem, Fac Sci, Qazvin, Iran
关键词
HETEROCYCLIC KETENE AMINALS; DERIVATIVES; MALONONITRILE; SCAFFOLDS; ISATIN;
D O I
10.1002/jhet.3326
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new series of isatin-based spiro-fused derivatives were prepared, via three-component reaction of N-alkyl-1-(methylthio)-2-nitroethenamine derived from the addition of various amines to nitroketene dithioacetal with isatin derivatives and 4-hydroxycoumarin in ethanol as a solvent at reflux. The significant advantages of this protocol include simple operation under mild conditions, easy purification, good yields, and catalyst-free approach.
引用
收藏
页码:2693 / 2697
页数:5
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