The basic chemical substances of three medicinal parts from Rhododendron molle G. Don

被引:8
作者
Song, Zhen-Fei [1 ]
Zheng, Xiang-Wei [1 ]
Xue, Qiu-Wen [1 ]
Qin, Jia-Xu [1 ]
Fang, Xin [1 ]
Liang, Shuang [1 ]
机构
[1] Shanghai Univ Tradit Chinese Med, Engn Res Ctr Modern Preparat Technol Tradit Chine, Minist Educ, Innovat Res Inst Tradit Chinese Med, Shanghai, Peoples R China
关键词
Rhododendron Molle; medicinal parts; traceability separation; characteristic peaks; basic chemical substances;
D O I
10.1080/14786419.2021.1986710
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Rhododendron Molle G. Don belongs to Ericaceae family. As a toxic traditional Chinese medicine, its roots, flowers, and fruit are often mixed and substituted arbitrarily to treat rheumatoid arthritis in clinic. To clarify the main chemical basis of each medicinal part, and provide sufficient scientific basis for clinical application, analysis using HPLC-ELSD of the roots, flowers, and fruit from R. molle was established, and characteristic chemical constituents of them were separated by tracking. The structures were determined by NMR methods. Finally, 16, 21, and 18 compounds were obtained from the roots, flowers, and fruit, respectively. Overall, 49 compounds were obtained, of which 25 were identified for the first time in R. molle. Meanwhile, among the obtained compounds, 12, 11, and 6 characteristic peaks were identified from the roots, flowers, and fruit, respectively. Thus, the basic chemical substances of the medicinal parts of R. molle were determined initially.
引用
收藏
页码:4498 / 4501
页数:4
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