Biostatistics Primer What a Clinician Ought to Know: Hazard Ratios

被引：53

作者：

Barraclough, Helen ^{[2
]}

Simms, Lorinda ^{[3
]}

Govindan, Ramaswamy ^{[1
,4
]}

机构：

[1] Washington Univ, Sch Med, Div Med Oncol, Alvin J Siteman Canc Ctr, St Louis, MO 63110 USA

[2] Eli Lilly & Co, Asia Pacific Stat Sci, Sydney, NSW, Australia

[3] Eli Lilly Canada Inc, Toronto, ON, Canada

[4] Washington Univ, Sch Med, Dept Med, Div Oncol, St Louis, MO 63110 USA

来源：

JOURNAL OF THORACIC ONCOLOGY | 2011年 / 6卷 / 06期

关键词：

Biostatistics; Hazard ratio; Proportional hazards; Survival analysis;

D O I：

10.1097/JTO.0b013e31821b10ab

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hazard ratios (HRs) are used commonly to report results from randomized clinical trials in oncology. However, they remain one of the most perplexing concepts for clinicians. A good understanding of HRs is needed to effectively interpret the medical literature to make important treatment decisions. This article provides clear guidelines to clinicians about how to appropriately interpret HRs. While this article focuses on the commonly used methods, the authors acknowledge that other statistical methods exist for analyzing survival data.

引用

页码：978 / 982

页数：5

共 7 条

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[7] PARTIAL RESIDUALS FOR THE PROPORTIONAL HAZARDS REGRESSION-MODEL
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