Demystifying Cell Cycle Arrest by HIV-1 Vif

被引：8
|
作者：
Salamango, Daniel J. [1 ,2 ]
Harris, Reuben S. [1 ,3 ]
机构：
[1] Univ Minnesota, Dept Biochem Mol Biol & Biophys, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Inst Mol Virol, Minneapolis, MN 55455 USA
[3] Univ Minnesota, Howard Hughes Med Inst, Minneapolis, MN 55455 USA
来源：
TRENDS IN MICROBIOLOGY | 2021年 / 29卷 / 05期
关键词：
LIGASE COMPLEX; PROTEINS; PHOSPHATASE;
D O I：
10.1016/j.tim.2021.01.001
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Although APOBEC3 degradation is the canonical function of HIV-1 Vif, this viral protein also induces potent cell cycle arrest through a newly defined mechanism. Here, we review recent advances in this area and propose that the scope of this activity may go beyond subversion of the host cell cycle.
引用
收藏
页码：381 / 384
页数：4
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