Composition of iodopropylideneglycerol: An example of the application of 2D NMR spectroscopy to structure elucidation

被引：0
作者：
Virgili, A [1 ]
Cervello, J [1 ]
机构：
[1] BOEHRINGER MANNHEIM SA,DEPT QUIM,E-08228 TERRASSA,SPAIN
来源：
MAGNETIC RESONANCE IN CHEMISTRY | 1996年 / 34卷 / 06期
关键词：
H-1; NMR; C-13; gradient-enhanced 2D NMR; iodopropylideneglycerol; dioxanes;
D O I：
10.1002/(SICI)1097-458X(199606)34:6<434::AID-OMR897>3.0.CO;2-O
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Using 1D and 2D NMR spectra, the compounds obtained, in a mixture, in the reaction of glycerol with iodine were identified as the two isomers (cis and trans) of 2-iodmethyl-5-hydroxymethyl-1,4-dioxane and the two isomers (cis and trans) of 2-iodomethyl-6-hydroxymethyl-1,4-dioxane. Thus, the composition of the pharmaceutical formulation named IPG has finally been established.
引用
收藏
页码：434 / 439
页数：6
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