Coronary artery endothelial protection after local delivery of 17β-estradiol

被引:0
作者
Tanguay, JF [1 ]
机构
[1] Montreal Heart Inst, Res Ctr, Montreal, PQ H1T 1C8, Canada
来源
ADVANCES IN HEART FAILURE | 2002年
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In the last decade, the predominant role of the endothelium in vascular healing after balloon injury and stent implantation has been better recognized. The endothelium regulates vascular tone, thrombosis, inflammation and cell proliferation (1-2). Endothelial dysfunction related to vascular injury may induce subsequent restenosis (3-4). Therefore, it may be important to improve endothelial recovery after angioplasty (PTCA) in order to reduce restenosis and improve clinical outcome.
引用
收藏
页码:87 / 89
页数:3
相关论文
共 11 条
[1]   Basic fibroblast growth factor release by human coronary artery endothelial cells is enhanced by matrix proteins, 17β-estradiol, and a PKC signaling pathway [J].
Albuquerque, MLC ;
Akiyama, SK ;
Schnaper, HW .
EXPERIMENTAL CELL RESEARCH, 1998, 245 (01) :163-169
[2]   Local delivery of 17-beta-estradiol decreases neointimal hyperplasia after coronary angioplasty in a porcine model [J].
Chandrasekar, B ;
Tanguay, JF .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (06) :1972-1978
[3]  
CHANDRASEKAR B, 2001, IN PRESS J AM COLL C
[4]   Randomized trial comparing intravenous nitroglycerin and heparin for treatment of unstable angina secondary to restenosis after coronary artery angioplasty [J].
Doucet, S ;
Malekianpour, M ;
Théroux, P ;
Bilodeau, L ;
Côté, G ;
de Guise, P ;
Dupuis, J ;
Joyal, M ;
Gosselin, G ;
Tanguay, JF ;
Juneau, M ;
Harel, F ;
Nattel, S ;
Tardif, JC ;
Lespérance, J .
CIRCULATION, 2000, 101 (09) :955-961
[5]   THE OBLIGATORY ROLE OF ENDOTHELIAL-CELLS IN THE RELAXATION OF ARTERIAL SMOOTH-MUSCLE BY ACETYLCHOLINE [J].
FURCHGOTT, RF ;
ZAWADZKI, JV .
NATURE, 1980, 288 (5789) :373-376
[6]  
Hyder SM, 1996, CANCER RES, V56, P3954
[7]   Enhanced endothelium-dependent relaxations after gene transfer of recombinant endothelial nitric oxide synthase to rabbit carotid arteries [J].
Kullo, IJ ;
Mozes, G ;
Schwartz, RS ;
Gloviczki, P ;
Tsutsui, M ;
Katusic, ZS ;
OBrien, T .
HYPERTENSION, 1997, 30 (03) :314-320
[8]   Endothelial dysfunction and collagen accumulation -: Two independent factors for restenosis and constrictive remodeling after experimental angioplasty [J].
Lafont, A ;
Durand, E ;
Samuel, JL ;
Besse, B ;
Addad, F ;
Lévy, BI ;
Desnos, M ;
Guérot, C ;
Boulanger, CM .
CIRCULATION, 1999, 100 (10) :1109-1115
[9]   Role of endothelial cells in restenosis after coronary angioplasty [J].
Meurice, T ;
Vallet, B ;
Bauters, C ;
Dupuis, B ;
Lablanche, JM ;
Bertrand, ME .
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 1996, 10 (03) :234-242
[10]   EFFECT OF A LOW-DOSE OF DIPYRIDAMOLE ON GLYCERYL TRINITRATE TOLERANCE IN HEALTHY-VOLUNTEERS [J].
TORFGARD, KE ;
AHLNER, J .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1993, 21 (04) :516-521