Evaluation of cognitive impairment in a population of patients with Parkinson's disease by means of the Mini Mental Parkinson test

被引:16
作者
Parrao-Díaz, T
Chaná-Cuevas, P
Juri-Claverías, C
Kunstmann, C
Tapia-Núñez, J
机构
[1] Univ Santiago Chile, CETRAM, Fac Ciencias Med, Santiago, Chile
[2] Catholic Univ Chile, Santiago, Chile
[3] Univ Chile, Unidad Neurol, Santiago, Chile
关键词
dementia; Minimental Parkinson; Minimental state examination; Parkinson disease;
D O I
10.33588/rn.4006.2004081
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction. Parkinson's disease (PD) is a neurodegenerative disorder in which motor symptoms are initially predominant; however; as the disease progresses, cognitive deterioration becomes more evident. Tests designed to detect cognitive impairment are therefore needed. Aims. The aim of the study was to assess the cognitive status of a population of patients with PD by means of the Mini Mental Parkinson test (MMP). Patients and methods. In 110 patients with idiopathic PD, with a mean age of 66.4 +/- 10.2 years and an average history of 8.8 +/- 5.8 years of the disease, the mean severity of the disease as measured by the unified PD rating scale (UPDRS-III) was 26.2 +/- 12.9. Results. There were 20 (18.2%) subjects with dementia according to DSM-IV criteria, with a score of 20.4 +/- 6.4 on the MMP Of the 90 patients who did not have dementia, 47 cases displayed cognitive impairment, without the presence of disorders affecting their activities of daily living, who scored 25.3 +/- 4.7 points on the MMP and 43 cases did not show airy kind of cognitive impairment, with 28.0 +/- 3.3 points on the MMP: these differences were statistically significant p < 0.001. Results according to age brackets showed a decrease in MMP with age and more especially so concerning memory functioning. As to severity, there is a cognitive decline, in particular with regard to memory orientation and abstraction. Conclusions. Cognitive capacity is seen to decline with age and the severity of the disease.
引用
收藏
页码:339 / 344
页数:6
相关论文
共 18 条
[1]   Performance on the dementia rating scale in Parkinson's disease with dementia and dementia with Lewy bodies: comparison with progressive supranuclear palsy and Alzheimer's disease [J].
Aarsland, D ;
Litvan, I ;
Salmon, D ;
Galasko, D ;
Wentzel-Larsen, T ;
Larsen, JP .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2003, 74 (09) :1215-1220
[2]   Specific alterations in attention in the early stages of Parkinson's disease [J].
Alonso-Prieto, E ;
Esteban, EM ;
Trujillo-Matienzo, C ;
Lara-Fernández, GE ;
Roussó-Viota, T ;
Cordero-Eiriz, A .
REVISTA DE NEUROLOGIA, 2003, 36 (11) :1015-1018
[3]  
Caparros D, 1994, J NEUROL NEUROSUR PS, V57, P1203
[4]   The role of the basal ganglia in monitorization of frontal lobe function [J].
Catalá-Barceló, J .
REVISTA DE NEUROLOGIA, 2002, 34 (04) :371-377
[5]   New tests for dementia [J].
Cummings, JL .
NEUROLOGY, 2000, 55 (11) :1601-1602
[6]   What causes mental dysfunction in Parkinson's disease? [J].
Emre, M .
MOVEMENT DISORDERS, 2003, 18 :S63-S71
[7]   Frontal lobes:: The executive brain [J].
Estévez-González, A ;
García-Sánchez, C ;
Barraquer-Bordas, L .
REVISTA DE NEUROLOGIA, 2000, 31 (06) :566-577
[8]  
Fahn S, 1987, Recent Dev. Park. Dis, P153
[9]   Hallucinations in Parkinson's disease -: Prevalence, phenomenology and risk factors [J].
Fénelon, G ;
Mahieux, F ;
Huon, R ;
Ziégler, M .
BRAIN, 2000, 123 :733-745
[10]   ACCURACY OF CLINICAL-DIAGNOSIS OF IDIOPATHIC PARKINSONS-DISEASE - A CLINICOPATHOLOGICAL STUDY OF 100 CASES [J].
HUGHES, AJ ;
DANIEL, SE ;
KILFORD, L ;
LEES, AJ .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1992, 55 (03) :181-184