Modeling protein complexes with BiGGER

被引：33

作者：

Krippahl, L ^{[1
]}

Moura, JJ ^{[1
]}

Palma, PN ^{[1
]}

机构：

[1] Univ Nova Lisboa, Fac Ciencias & Tecnol, Ctr Quim Fina & Biotecnol, Dept Quim,REQUIMTE, P-2825114 Monte De Caparica, Portugal

来源：

PROTEINS-STRUCTURE FUNCTION AND GENETICS | 2003年 / 52卷 / 01期

关键词：

D O I：

10.1002/prot.10387

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This article describes the method and results of our participation in the Critical Assessment of PRediction of Interactions (CAPRI) experiment, using the protein docking program BiGGER (Bimolecular complex Generation with Global Evaluation and Ranking) (Palma et al., Proteins 2000;39: 372-384). Of five target complexes (CAPRI targets 2, 4, 5, 6, and 7), only one was successfully predicted (target 6), but BiGGER generated reasonable models for targets 4, 5, and 7, which could have been identified if additional biochemical information had been available. (C) 2003 Wiley-Liss, Inc.

引用

页码：19 / 23

页数：5

共 12 条

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