Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives

被引：13

作者：

Sekularac, Gavrilo M. ^{[1
]}

Nikolic, Jasmina B. ^{[2
]}

Petrovic, Predrag ^{[3
]}

Bugarski, Branko ^{[3
]}

Durovic, Boban ^{[4
]}

Drmanic, Sasa Z. ^{[2
]}

机构：

[1] Univ Belgrade, Inst Chem Technol & Met, Belgrade 11000, Serbia

[2] Univ Belgrade, Fac Technol & Met, Dept Organ Chem, Belgrade 11000, Serbia

[3] Univ Belgrade, Fac Technol & Met, Dept Chem Engn, Belgrade 11000, Serbia

[4] Fac Tech Sci, Kosovska Mitrovica 38220, Serbia

来源：

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY | 2014年 / 79卷 / 11期

关键词：

isatin derivatives; Schiff bases; antimicrobial activity; antioxidative activity; POTENTIAL ANTICONVULSANTS; ANTIBACTERIAL ACTIVITY; AGENTS; THIOSEMICARBAZONES; CONDENSATION;

D O I：

10.2298/JSC140709084S

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods. Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungus. The antioxidative activity of the synthesized compounds was also determined. Some of the compounds showed significant activity against the selected strains of microorganisms and antioxidative activity.

引用

页码：1347 / 1354

页数：8

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