Design of Metallic Lattices for Bone Implants by Additive Manufacturing

被引:4
作者
Barba, Daniel [1 ,2 ]
Reed, Roger C. [1 ,3 ]
Alabort, Enrique [4 ]
机构
[1] Univ Oxford, Dept Mat, Parks Rd, Oxford OX1 3PH, England
[2] Univ Politecn Madrid, Dept Aerosp Mat, ETSIAE, Madrid 28040, Spain
[3] Univ Oxford, Dept Engn Sci, Parks Rd, Oxford OX1 3PJ, England
[4] OxMet Technol, 15 Oxford Ind Pk, Yarnton OX5 1QU, England
来源
TMS 2020 149TH ANNUAL MEETING & EXHIBITION SUPPLEMENTAL PROCEEDINGS | 2020年
关键词
Lattice structures; Topological optimisation; Mechanical properties of AM materials; Manufacturability; ORTHOPEDIC IMPLANTS; MECHANICAL-PROPERTIES; TOPOLOGICAL DESIGN; SCAFFOLDS; BEHAVIOR;
D O I
10.1007/978-3-030-36296-6_69
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A broad range of synthetic trabecular-like metallic lattices is 3D printed in Ti-6Al-4V by SLM. The aim is to propose new conceptual types of implant structures for superior biomechanical matching and osseo-integration: synthetic bone. Systematic evaluation is then carried out: (i) their accuracy is characterised using HR X-ray tomography, to assess deviations from the original geometrical design intent and (ii) the mechanical properties-stiffness and strength-are experimentally measured and compared. Finally, this new knowledge is synthesised in a conceptual framework in the form of implant design maps, to define the processing conditions of bone tailored substitutes. The design criteria emphasise (a) the bone stiffness matching, (b) preferred range of pore structure for bone ingrowth, (c) manufacturability, and (d) choice of inherent materials properties for durable implants. The power of this framework is demonstrated in the design of a prototype spine fusion device.
引用
收藏
页码:745 / 759
页数:15
相关论文
共 28 条
[21]   The effect of pore geometry on the in vitro biological behavior of human periosteum-derived cells seeded on selective laser-melted Ti6Al4V bone scaffolds [J].
Van Bael, S. ;
Chai, Y. C. ;
Truscello, S. ;
Moesen, M. ;
Kerckhofs, G. ;
Van Oosterwyck, H. ;
Kruth, I. -P. ;
Schrooten, J. .
ACTA BIOMATERIALIA, 2012, 8 (07) :2824-2834
[22]   Micro-CT-based improvement of geometrical and mechanical controllability of selective laser melted Ti6Al4V porous structures [J].
Van Bael, S. ;
Kerckhofs, G. ;
Moesen, M. ;
Pyka, G. ;
Schrooten, J. ;
Kruth, J. P. .
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING, 2011, 528 (24) :7423-7431
[23]   Study on the designing rules and processability of porous structure based on selective laser melting (SLM) [J].
Wang, Di ;
Yang, Yongqiang ;
Liu, Ruicheng ;
Xiao, Dongming ;
Sun, Jianfeng .
JOURNAL OF MATERIALS PROCESSING TECHNOLOGY, 2013, 213 (10) :1734-1742
[24]   Topological design and additive manufacturing of porous metals for bone scaffolds and orthopaedic implants: A review [J].
Wang, Xiaojian ;
Xu, Shanqing ;
Zhou, Shiwei ;
Xu, Wei ;
Leary, Martin ;
Choong, Peter ;
Qian, M. ;
Brandt, Milan ;
Xie, Yi Min .
BIOMATERIALS, 2016, 83 :127-141
[25]   Effects of build orientation and heat treatment on the microstructure and mechanical properties of selective laser melted Ti6Al4V lattice structures [J].
Wauthle, Ruben ;
Vrancken, Bey ;
Beynaerts, Britt ;
Jorissen, Karl ;
Schrooten, Jan ;
Kruth, Jean-Pierre ;
Van Humbeeck, Jan .
ADDITIVE MANUFACTURING, 2015, 5 :77-84
[26]   Ti-6Al-4V triply periodic minimal surface structures for bone implants fabricated via selective laser melting [J].
Yan, Chunze ;
Hao, Liang ;
Hussein, Ahmed ;
Young, Philippe .
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2015, 51 :61-73
[27]   Bone tissue regeneration: the role of scaffold geometry [J].
Zadpoor, Amir A. .
BIOMATERIALS SCIENCE, 2015, 3 (02) :231-245
[28]   Topological design, permeability and mechanical behavior of additively manufactured functionally graded porous metallic biomaterials [J].
Zhang, Xiang-Yu ;
Fang, Gang ;
Leeflang, Sander ;
Zadpoor, Amir A. ;
Zhou, Jie .
ACTA BIOMATERIALIA, 2019, 84 :437-452