Recognizing the ethical implications of stem cell research: A call for broadening the scope

被引:20
作者
Assen, Lars S. [1 ]
Jongsma, Karin R. [1 ]
Isasi, Rosario [2 ,3 ]
Tryfonidou, Marianna A. [4 ]
Bredenoord, Annelien L. [1 ]
机构
[1] Univ Med Ctr Utrecht, Dept Med Humanities, Julius Ctr Hlth Sci & Primary Care, NL-3508 GA Utrecht, Netherlands
[2] Univ Miami, Miller Sch Med, Dr John T Macdonald Fdn Dept Human Genet, Miami, FL USA
[3] Univ Miami, Miller Sch Med, John P Hussman Inst Human Genom, Miami, FL USA
[4] Univ Utrecht, Fac Vet Med, Dept Clin Sci, NL-3584 CM Utrecht, Netherlands
来源
STEM CELL REPORTS | 2021年 / 16卷 / 07期
关键词
RESPONSIBILITY; MEDICINE;
D O I
10.1016/j.stemcr.2021.05.021
中图分类号
Q813 [细胞工程];
学科分类号
摘要
The ethical implications of stem cell research are often described in terms of risks, side effects, safety, and therapeutic value, which are examples of so-called hard impacts. Hard impacts are typically measurable and quantifiable. To understand the broader spectrum of ethical implications of stem cell research on science and society, it is equally important to recognize soft impacts. Soft impacts are the effects on behavior, experiences, actions, moral values, and social structures; these are often indirect effects of stem cell research. The combined notions of hard and soft impacts offer a broader way of thinking about the social and ethical implications of stem cell research and can help to steer stem cell research into a sociable desirable direction. Soft impacts enable researchers to become more aware of the broad range of significant implications involved in their work and deserve equal attention for understanding such ethical and societal effects of stem cell research.
引用
收藏
页码:1656 / 1661
页数:6
相关论文
共 22 条
  • [1] Andrews PW, 2015, REGEN MED, V10, P1, DOI [10.2217/rme.14.93, 10.2217/RME.14.93]
  • [2] Human tissues in a dish: The research and ethical implications of organoid technology
    Bredenoord, Annelien L.
    Clevers, Hans
    Knoblich, Juergen A.
    [J]. SCIENCE, 2017, 355 (6322)
  • [3] Confronting stem cell hype
    Caulfield, Timothy
    Sipp, Douglas
    Murry, Charles E.
    Daley, George Q.
    Kimmelman, Jonathan
    [J]. SCIENCE, 2016, 352 (6287) : 776 - 777
  • [4] Regulation or responsibility? Autonomy, moral imagination, and engineering
    Coeckelbergh, M
    [J]. SCIENCE TECHNOLOGY & HUMAN VALUES, 2006, 31 (03) : 237 - 260
  • [5] Organoids
    de Souza, Natalie
    [J]. NATURE METHODS, 2018, 15 (01) : 23 - 23
  • [6] Allogeneic Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single-Stage Cartilage Repair in Humans upon Mixture with Recycled Autologous Chondrons
    de Windt, Tommy S.
    Vonk, Lucienne A.
    Slaper-Cortenbach, Ineke C. M.
    van den Broek, Marcel P. H.
    Nizak, Razmara
    van Rijen, Mattie H. P.
    de Weger, Roel A.
    Dhert, Wouter J. A.
    Saris, Daniel B. F.
    [J]. STEM CELLS, 2017, 35 (01) : 256 - 264
  • [7] Studying the lay of the land: views and experiences of professionals in the translational pluripotent stem cell field
    Habets, Michelle G. J. L.
    van Delden, Johannes J. M.
    Bredenoord, Annelien L.
    [J]. REGENERATIVE MEDICINE, 2016, 11 (01) : 63 - 71
  • [8] Is Individualized Medicine More Cost-Effective? A Systematic Review
    Hatz, Maximilian H. M.
    Schremser, Katharina
    Rogowski, Wolf H.
    [J]. PHARMACOECONOMICS, 2014, 32 (05) : 443 - 455
  • [9] Horng Sam, 2003, IRB, V25, P11, DOI 10.2307/3564408
  • [10] The bioethics of stem cell research and therapy
    Hyun, Insoo
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (01) : 71 - 75