Physicochemical and pharmacokinetic properties of COMT inhibitors

被引:1
作者
Forsberg, Markus [1 ]
机构
[1] Univ Kuopio, Dept Pharmacol & Toxicol, FIN-70211 Kuopio, Finland
关键词
D O I
10.1016/j.ejps.2008.02.018
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:S8 / S8
页数:1
相关论文
共 50 条
  • [41] Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning
    Aoki, Toshihiro
    Hyohdoh, Ikumi
    Furuichi, Noriyuki
    Ozawa, Sawako
    Watanabe, Fumio
    Matsushita, Masayuki
    Sakaitani, Masahiro
    Morikarni, Kenji
    Takanashi, Kenji
    Harada, Naoki
    Tomii, Yasushi
    Shiraki, Koji
    Furumoto, Kentaro
    Tabo, Mitsuyasu
    Yoshinari, Kiyoshi
    Ori, Kazutomo
    Aoki, Yuko
    Shimma, Nobuo
    Iikura, Hitoshi
    ACS MEDICINAL CHEMISTRY LETTERS, 2014, 5 (04): : 309 - 314
  • [42] Potential risks of central active COMT inhibitors
    Kuhn, W
    Woitalla, D
    Russ, H
    Gerlach, M
    Müller, T
    AKTUELLE NEUROLOGIE, 1998, 25 : S277 - S278
  • [43] COMT Inhibitors in the Management of Parkinson’s Disease
    Margherita Fabbri
    Joaquim J. Ferreira
    Olivier Rascol
    CNS Drugs, 2022, 36 : 261 - 282
  • [44] Ogipeptins, novel inhibitors of LPS: physicochemical properties and structural elucidation
    Yuki Hirota-Takahata
    Shiho Kozuma
    Nahoki Kuraya
    Daisuke Fukuda
    Mutsuo Nakajima
    Toshio Takatsu
    Osamu Ando
    The Journal of Antibiotics, 2017, 70 : 84 - 89
  • [45] Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-RafV600E kinase with favorable physicochemical and pharmacokinetic properties
    Ren, Li
    Laird, Ellen R.
    Buckmelter, Alex J.
    Dinkel, Victoria
    Gloor, Susan L.
    Grina, Jonas
    Newhouse, Brad
    Rasor, Kevin
    Hastings, Gregg
    Gradl, Stefan N.
    Rudolph, Joachim
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (02) : 1165 - 1168
  • [46] Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties
    Hill, Matthew D.
    Fang, Haiquan
    Norris, Derek
    Delucca, George, V
    Huang, Hong
    DeBenedetto, Mikkel
    Quesnelle, Claude
    Schmitz, William D.
    Tokarski, John S.
    Sheriff, Steven
    Yan, Chunhong
    Fanslau, Caroline
    Haarhoff, Zuzana
    Huang, Christine
    Kramer, Melissa
    Madari, Shilpa
    Menard, Krista
    Monereau, Laura
    Morrison, John
    Raghavan, Nirmala
    Shields, Eric E.
    Simmermacher-Mayer, Jean
    Sinz, Michael
    Tye, Ching Kim
    Westhouse, Richard
    Xie, Chunshan
    Zhang, Haiying
    Zhang, Lisa
    Zvyaga, Tatyana
    Lee, Francis
    Gavai, Ashvinikumar, V
    Degnan, Andrew P.
    ACS MEDICINAL CHEMISTRY LETTERS, 2022, 13 (07): : 1165 - 1171
  • [47] Novel Hinge Binder Improves Activity and Pharmacokinetic Properties of BRAF Inhibitors
    Zambon, Alfonso
    Menard, Delphine
    Suijkerbuijk, Bart M. J. M.
    Niculescu-Duvaz, Ion
    Whittaker, Steven
    Niculescu-Duvaz, Dan
    Nourry, Arnaud
    Davies, Lawrence
    Manne, Helen A.
    Lopes, Filipa
    Preece, Natasha
    Hedley, Douglas
    Ogilvie, Lesley M.
    Kirk, Ruth
    Marais, Richard
    Springer, Caroline J.
    JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (15) : 5639 - 5655
  • [48] Physicochemical and pharmacokinetic characteristics of cationic liposomes
    Yeeprae, W
    Kawakami, S
    Suzuki, S
    Yamashita, F
    Hashida, M
    PHARMAZIE, 2006, 61 (02): : 102 - 105
  • [49] Physicochemical and pharmacokinetic properties of polymeric films loaded with cisplatin for the treatment of malignant pleural mesothelioma
    Sonvico, Fabio
    Barbieri, Stefano
    Colombo, Paolo
    Mucchino, Claudio
    Barocelli, Elisabetta
    Cantoni, Anna Maria
    Cavazzoni, Andrea
    Petronini, Pier Giorgio
    Rusca, Michele
    Carbognani, Paolo
    Ampollini, Luca
    JOURNAL OF THORACIC DISEASE, 2018, 10 : S194 - S206
  • [50] Simulation of Physicochemical and Pharmacokinetic Properties of Vitamin D3and Its Natural Derivatives
    Deb, Subrata
    Reeves, Anthony Allen
    Lafortune, Suki
    PHARMACEUTICALS, 2020, 13 (08) : 1 - 16