Chronic Hypersensitivity Pneumonitis

被引：86
|
作者：
Costabel, Ulrich [1 ]
Bonella, Francesco [1 ]
Guzman, Josune [2 ]
机构：
[1] Univ Hosp, Ruhrlandklin, Dept Pneumol Allergy, D-45239 Essen, Germany
[2] Ruhr Univ Bochum, BG Kliniken Bergmannsheil, Inst Pathol, D-44789 Bochum, Germany
来源：
CLINICS IN CHEST MEDICINE | 2012年 / 33卷 / 01期
关键词：
Hypersensitivity pneumonitis; Farmer's lung; Bird fancier's disease; HRCT; Histopathology; Prognosis; EXTRINSIC ALLERGIC ALVEOLITIS; BRONCHOALVEOLAR LAVAGE FLUID; NECROSIS-FACTOR-ALPHA; PIGEON-BREEDERS LUNG; BIRD FANCIERS LUNG; HIGH-RESOLUTION CT; DRY SAUSAGE MOLD; FARMERS LUNG; PULMONARY-FUNCTION; GENE POLYMORPHISMS;
D O I：
10.1016/j.ccm.2011.12.004
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Hypersensitivity pneumonitis (HP) is a complex syndrome caused by the inhalation of environmental antigens. Chronic HP may mimic other fibrotic lung diseases, such as idiopathic pulmonary fibrosis. Recognition of the antigen is important for diagnosis; avoidance of further exposure is critical for treatment. Fibrosis on biopsy or high-resolution computed tomography is a predictor of increased mortality. Additional research is needed to understand why the disease develops only in a minority of exposed individuals and why cases of chronic HP may progress without further antigen exposure.
引用
收藏
页码：151 / +
页数：14
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