Assessing omega-3 fatty acid supplementation during pregnancy and lactation to optimize maternal mental health and childhood cognitive development

被引：3

作者：

Klemens, Chelsea M. ^{[2
]}

Salari, Kataneh ^{[3
]}

Mozurkewich, Ellen L. ^{[1
]}

机构：

[1] 1 Univ New Mexico, Sch Med, Dept Obstet & Gynecol, Div Maternal Fetal Med, Albuquerque, NM 87131 USA

[2] Michigan State Univ, Coll Human Med, E Lansing, MI 48824 USA

[3] Univ Michigan, Dept Obstet & Gynecol, Div Maternal Fetal Med, Ann Arbor, MI 48109 USA

来源：

CLINICAL LIPIDOLOGY | 2012年 / 7卷 / 01期

基金：

美国国家卫生研究院;

关键词：

child development; mental health; omega-3 fatty acid; placenta; POLYUNSATURATED FATTY-ACIDS; FISH-OIL SUPPLEMENTATION; DOCOSAHEXAENOIC ACID; PERINATAL DEPRESSION; ARACHIDONIC-ACID; NEURODEVELOPMENTAL OUTCOMES; EICOSAPENTAENOIC ACID; POSTPARTUM DEPRESSION; SEAFOOD CONSUMPTION; VISUAL FUNCTION;

D O I：

10.2217/CLP.12.1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The omega-3 fatty acid, docosahexaenoic acid, is an important building block of the CNS, and its availability during pregnancy and lactation may influence maternal mental health and, later, childhood developmental outcomes. Epidemiological and observational studies have supported a role for omega-3 fatty acids in optimizing child development and maternal mental health. However, results of randomized intervention studies have not consistently shown beneficial effects for omega-3 fatty acid supplementation during pregnancy and lactation. This review summarizes the biological plausibility, as well as the available evidence from observational and randomized controlled trials, of omega-3 supplementation in pregnancy and lactation.

引用

页码：93 / 109

页数：17

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