Sildenafil Therapy for Interferon-β-1a-Induced Pulmonary Arterial Hypertension: A Case Report

被引：27

作者：

Caravita, Sergio ^{[1
]}

Secchi, Maria Beatrice ^{[1
]}

Wu, Sheng Chin ^{[1
]}

Pierini, Simona ^{[1
]}

Paggi, Anita ^{[1
]}

机构：

[1] Azienda Osped Ist Clin Perfezionamento, Pulm Hypertens Ctr, Bassini Hosp, IT-20092 Milan, Italy

来源：

CARDIOLOGY | 2011年 / 120卷 / 04期

关键词：

Pulmonary arterial hypertension; Interferon-beta-1a; Interferons; Multiple sclerosis; Sildenafil; GUIDELINES;

D O I：

10.1159/000335064

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Interferon (IFN) therapy is nowadays widely used in clinical practice. In the literature, there are very few reports of the association between IFN therapy and pulmonary arterial hypertension (PAH), and current guidelines do not mention IFNs as a risk factor for PAH. We describe a patient with multiple sclerosis who developed severe PAH after treatment with IFN-beta-1a and the clinical response to sildenafil. Furthermore, we stress the need to further investigate the link between IFNs and PAH. Copyright (C) 2012 S. Karger AG, Basel

引用

页码：187 / 189

页数：3

共 6 条

[1] Irreversible Pulmonary Hypertension Associated with the use of Interferon Alpha for Chronic Hepatitis C [J].