Seroprevalence of IgG antibodies to the chlamydia-like microorganism 'Simkania Z' by ELISA

被引:40
作者
Friedman, MG
Galil, A
Greenberg, S
Kahane, S
机构
[1] Ben Gurion Univ Negev, Fac Hlth Sci, Dept Virol, IL-84105 Beer Sheva, Israel
[2] Ben Gurion Univ Negev, Fac Hlth Sci, Soroka Med Ctr, Inst Child Dev, IL-84105 Beer Sheva, Israel
[3] Soroka Med Ctr, Dept Internal Med, IL-84101 Beer Sheva, Israel
关键词
D O I
10.1017/S095026889800185X
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The newly described microorganism 'Simkania Z', related to the Chlamydiae, has been shown to be associated with bronchiolitis in infants and community acquired pneumonia in adults. The prevalence of infection in the general population is unknown. A simple ELISA assay for the detection of serum IgG antibodies to 'Simkania Z' was used to determine the prevalence of such antibodies in several population samples in southern Israel (the Negev). The groups tested included 94 medical and nursing students, 100 unselected blood donors, 106 adult members of a Negev kibbutz (communal agricultural settlement), and 45 adult Bedouin, residents of the Negev. IgG antibodies to 'Simkania Z' were found in 55-80 % of these presumably healthy individuals, independently of antibodies to Chlamydia trachomatis and Chlamydia pneumoniae. The Bedouin had a seropositivity rate of 80 %, while all other groups had rates of between 55 and 64%. These results indicate that 'Simkania Z' infection is probably common in southern Israel.
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页码:117 / 123
页数:7
相关论文
共 24 条
[1]   Obligate intracellular bacterial parasites of acanthamoebae related to Chlamydia spp. [J].
Amann, R ;
Springer, N ;
Schonhuber, W ;
Ludwig, W ;
Schmid, EN ;
Muller, KD ;
Michel, R .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1997, 63 (01) :115-121
[2]   Limits of the microimmunofluorescence test and advantages of immunoblotting in the diagnosis of chlamydiosis [J].
Biendo, M ;
Eb, F ;
Lefebvre, JF ;
Orfila, J .
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1996, 3 (06) :706-709
[3]   Chlamydia-like obligate parasite of free-living amoebae [J].
Birtles, RJ ;
Rowbotham, TJ ;
Storey, C ;
Marrie, TJ ;
Raoult, D .
LANCET, 1997, 349 (9056) :925-926
[4]   PURIFICATION AND PARTIAL CHARACTERIZATION OF THE MAJOR OUTER-MEMBRANE PROTEIN OF CHLAMYDIA-TRACHOMATIS [J].
CALDWELL, HD ;
KROMHOUT, J ;
SCHACHTER, J .
INFECTION AND IMMUNITY, 1981, 31 (03) :1161-1176
[5]   GROWTH OF LEGIONELLA-PNEUMOPHILA IN ACANTHAMOEBA-CASTELLANII ENHANCES INVASION [J].
CIRILLO, JD ;
FALKOW, S ;
TOMPKINS, LS .
INFECTION AND IMMUNITY, 1994, 62 (08) :3254-3261
[6]   The ribosomal intergenic spacer and domain I of the 23S rRNA gene are phylogenetic markers for Chlamydia spp. [J].
Everett, KDE ;
Andersen, AA .
INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1997, 47 (02) :461-473
[7]  
FRIEDMAN MG, 1997, OPPORT PATHOGENS, V9, P43
[8]   SERUM REACTIVITY TO CHLAMYDIA-TRACHOMATIS AND C-PNEUMONIAE ANTIGENS IN PATIENTS WITH DOCUMENTED INFECTION AND IN HEALTHY-CHILDREN BY MICROIMMUNOFLUORESCENCE AND IMMUNOBLOTTING TECHNIQUES [J].
GONEN, R ;
SHEMERAVNI, Y ;
CSANGO, PA ;
SAROV, B ;
FRIEDMAN, MG .
APMIS, 1993, 101 (09) :719-726
[9]   DIFFERENTIATION OF PRIMARY FROM NONPRIMARY GENITAL HERPESVIRUS INFECTIONS BY DETECTION OF POLYMERIC IMMUNOGLOBULIN-A ACTIVITY [J].
HASHIDO, M ;
KAWANA, T ;
INOUYE, S .
JOURNAL OF CLINICAL MICROBIOLOGY, 1989, 27 (11) :2609-2611
[10]  
Hedman K., 1993, REV MED MICROBIOL, V4, P123, DOI DOI 10.1111/J.1469-0691.1996.TB00196.X