An Efficient Metal-Free Method for the Denitrosation of Aryl N-Nitrosamines at Room Temperature

被引：28

作者：

Chaudhary, Priyanka ^{[1
]}

Korde, Rishi ^{[1
]}

Gupta, Surabhi ^{[1
]}

Sureshbabu, Popuri ^{[2
]}

Sabiah, Shahulhameed ^{[2
]}

Kandasamy, Jeyakumar ^{[1
]}

机构：

[1] Indian Inst Technol BHU, Dept Chem, Varanasi 221005, Uttar Pradesh, India

[2] Pondicherry Univ, Dept Chem, Pondicherry 605014, India

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 03期

关键词：

N-nitrosamine; denitrosation; metal-free; triethylsilane; iodine; green chemistry; REDUCTIVE DENITROSATION; SECONDARY-AMINES; NITROSO; NITROSOANILINES; ACTIVATION; CLEAVAGE; HYDRIDE; MILD; BOND; TRIETHYLSILANE;

D O I：

10.1002/adsc.201701047

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A simple and practical method for the denitrosation of aryl N-nitrosamines to secondary amines is reported under metal-free conditions using iodine and triethylsilane. Several reduction-susceptible functional groups such as alkene, alkyne, nitrile, nitro, aldehyde, ketone and ester were found to be very stable during the denitrosation, which is remarkable. Broad substrate scope, room temperature reactions and excellent yields are the additional features of the current methodology.

引用

页码：556 / 561

页数：6

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