Synthesis and radioprotective activity of some threo-D,L-phenylserine derivatives

被引：0

作者：

Dirvianskyte, Nijole ^{[1
]}

Leonaviciene, Laima ^{[2
]}

Bradunaite, Ruta ^{[2
]}

机构：

[1] Lithuania Acad Sci, Inst Biochem, LT-08662 Vilnius, Lithuania

[2] Vilnius State Univ, Med Clin, Inst Expt, LT-01102 Vilnius, Lithuania

来源：

CHEMIJA | 2007年 / 18卷 / 04期

关键词：

N-acyl-threo-D; L-phenylserine derivatives; radioprotective activity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of 2-aminothiazolinium, 2-mercaptoethylamine and 2-amino-1-phenylethanol salts of N-acyl-threo-D,L-phenylserine was accomplished. Fourteen derivatives were investigated for their toxicity and radioprotective effect on mice. 2-aminothiazolinium salt of N-formyl-threo-D,L-Phenylserine at a dose of 250 mg/kg was the most potent radioprotector.

引用

页码：44 / 47

页数：4

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