Presence of PAF-acether in human blood after thin-layer chromatography, but not after high-performance liquid chromatography purification

被引：0
作者：
Izzo, AA [1 ]
Benveniste, J [1 ]
机构：
[1] INSERM,U200,F-92140 CLAMART,FRANCE
来源：
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS | 1996年 / 36卷 / 04期
关键词：
HPLC; TLC; lipopaf; phosphatidylcholine;
D O I：
10.1016/S1056-8719(96)00129-3
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
After HPLC purification of human blood extracts, paf-acether (paf) was found exclusively as a lipoprotein-bound compound (lipopaf), whereas free-paf was absent. When the same samples (or lipopaf recovered from HPLC) were purified by TLC, both free-paf and lipopaf were detected. The free-paf detected in blood samples could thus result from lipopaf dissociation during TLC purification. (C) 1996 Elsevier Science Inc.
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页码：219 / 221
页数：3
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