Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications

被引：125
作者：
Chen, Yan [1 ]
Lu, Yao [1 ]
Lee, Robert J. [2 ]
Xiang, Guangya [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Sch Pharm, Tongji Med Coll, Hangkong Rd 13, Wuhan 430030, Hubei, Peoples R China
[2] Ohio State Univ, Div Pharmaceut & Pharmacol, Columbus, OH 43210 USA
来源：
INTERNATIONAL JOURNAL OF NANOMEDICINE | 2020年 / 15卷
基金：
中国国家自然科学基金;
关键词：
curcumin; nanoformulations; bioavailability; nanoparticles; therapy; MESOPOROUS SILICA NANOPARTICLES; SOLID LIPID NANOPARTICLES; DRUG-DELIVERY SYSTEM; BOVINE SERUM-ALBUMIN; LOADED PLGA NANOPARTICLES; IN-VITRO; POLYMERIC NANOPARTICLES; CHITOSAN NANOPARTICLES; LIPOSOMAL CURCUMIN; CONTROLLED-RELEASE;
D O I：
10.2147/IJN.S210320
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic application of curcumin is limited by its extremely low solubility in aqueous buffer, instability in body fluids, and rapid metabolism. Nano delivery system has shown excellent potential to improve the solubility, biocompatibility and therapeutic effect of curcumin. In this review, we focus on the recent development of nano encapsulated curcumin and its potential for biomedical applications.
引用
收藏
页码：3099 / 3120
页数：22
相关论文
共 50 条
  • [31] Magnetically Actuated Droplet Manipulation and Its Potential Biomedical Applications
    Huang, Guoyou
    Li, Moxiao
    Yang, Qingzhen
    Li, Yuhui
    Liu, Hao
    Yang, Hui
    Xu, Feng
    ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (02) : 1155 - 1166
  • [32] Accelerated Simple Preparation of Curcumin-Loaded Silk Fibroin/Hyaluronic Acid Hydrogels for Biomedical Applications
    Chaala, Mohamed
    Sebba, Fatima Zohra
    Fuster, Marta G.
    Moulefera, Imane
    Montalban, Mercedes G.
    Carissimi, Guzman
    Villora, Gloria
    POLYMERS, 2023, 15 (03)
  • [33] Oral Delivery of Curcumin Using Silk Nano- and Microparticles
    Wu, Jianbing
    Wang, Jing
    Zhang, Jue
    Zheng, Zhaozhu
    Kaplan, David L.
    Li, Gang
    Wang, Xiaoqin
    ACS BIOMATERIALS SCIENCE & ENGINEERING, 2018, 4 (11): : 3885 - 3894
  • [34] Biological Potential and Bioaccessibility of Encapsulated Curcumin into Cetyltrimethylammonium Bromide Modified Cellulose Nanocrystals
    Casanova, Francisca
    Pereira, Carla
    Ribeiro, Alessandra
    Castro, Pedro
    Freixo, Ricardo
    Martins, Eva
    Tavares-Valente, Diana
    Fernandes, Joao
    Pintado, Manuela
    Ramos, Oscar
    PHARMACEUTICALS, 2023, 16 (12)
  • [35] Potential Role of Curcumin and Its Nanoformulations to Treat Various Types of Cancers
    Kabir, Md. Tanvir
    Rahman, Md. Habibur
    Akter, Rokeya
    Behl, Tapan
    Kaushik, Deepak
    Mittal, Vineet
    Pandey, Parijat
    Akhtar, Muhammad Furqan
    Saleem, Ammara
    Albadrani, Ghadeer M.
    Kamel, Mohamed
    Khalifa, Shaden A. M.
    El-Seedi, Hesham R.
    Abdel-Daim, Mohamed M.
    BIOMOLECULES, 2021, 11 (03) : 1 - 39
  • [36] Recent developments in curcumin and curcumin based polymeric materials for biomedical applications: A review
    Mahmood, Kashif
    Zia, Khalid Mahmood
    Zuber, Mohammad
    Salman, Mahwish
    Anjum, Muhammad Naveed
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2015, 81 : 877 - 890
  • [37] Biomedical Applications of Cell Membrane-Based Biomimetic Nano-Delivery System
    Zhang, Dexin
    Wang, Guodong
    Ma, Ningyi
    Yuan, Ziyang
    Dong, Yuqin
    Huang, Xin
    Qiao, Haishi
    Ren, Ke
    ADVANCED THERAPEUTICS, 2024, 7 (02)
  • [38] POLYMER MAGNETIC PARTICLES IN BIOMEDICAL APPLICATIONS
    Balaita, Lacramioara
    Popa, Marcel
    REVUE ROUMAINE DE CHIMIE, 2009, 54 (03) : 185 - 199
  • [39] Potential of Curcumin and Its Analogs in Glioblastoma Therapy
    Nowacka, Agnieszka
    Ziolkowska, Ewa
    Smuczynski, Wojciech
    Bozilow, Dominika
    Sniegocki, Maciej
    ANTIOXIDANTS, 2025, 14 (03)
  • [40] Engineering of pectin-dopamine nano-conjugates for carrying ruthenium complex: A potential tool for biomedical applications
    Diao, Jiajing
    Bai, Feng
    Wang, Ying
    Han, Qianqian
    Xu, Xi
    Zhang, Hongmei
    Luo, Qiang
    Wang, Yanqing
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2019, 191 : 135 - 142
12345