A Selective Simultaneous Determination of Levodopa and Serotonin Using a Glassy Carbon Electrode Modified with Multiwalled Carbon Nanotube/Chitosan Composite

被引：56
作者：
Babaei, Ali [1 ,2 ]
Babazadeh, M. [1 ]
机构：
[1] Univ Arak, Dept Chem, Arak, Iran
[2] Univ Arak, Res Ctr Nanotechnol, Arak, Iran
来源：
ELECTROANALYSIS | 2011年 / 23卷 / 07期
关键词：
Levodopa; Serotonin; Chitosan; Multiwalled carbon nanotubes; Modified glassy carbon; PERFORMANCE LIQUID-CHROMATOGRAPHY; KINETIC-SPECTROPHOTOMETRIC DETERMINATION; NANOTUBES-CHITOSAN COMPOSITE; L-DOPA; RAT-BRAIN; ELECTROCHEMICAL DETECTION; FLUORESCENCE DETECTION; RAPID-DETERMINATION; ASCORBIC-ACID; HUMAN PLASMA;
D O I：
10.1002/elan.201000755
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A glassy carbon electrode (GCE) modified with carbon nanotube/chitosan (MWCNTs-CHT/GCE) was used for the sensitive voltammetric determination of levodopa (Lev) and serotonin (Ser). The measurements were carried out using cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA). Under the optimum conditions the electrode provides a linear response versus Lev and Ser concentrations in the range of 2.0-220.0 mu M and 0.5- 130.0 mu M, respectively, using DPV. The modified electrode was satisfactorily used for determination of Lev and Ser in human serum and urine with satisfactory results.
引用
收藏
页码：1726 / 1735
页数：10
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