The two hit hypothesis in the antiphospholipid syndrome: acute ischaemic heart involvement after valvular replacement despite anticoagulation in a patient with secondary APS

被引：22

作者：

Bordin, G

Boldorini, R

Meroni, PL

机构：

[1] Presidio Osped Bassini, Azienda Osped S Gerardo, Dept Internal Med, Milan, Italy

[2] Osped Maggiore La Carita, Pathol Serv, Novara, Italy

[3] Univ Milan, Dept Internal Med, Allergy & Clin Immunol Unit, Milan, Italy

来源：

LUPUS | 2003年 / 12卷 / 11期

关键词：

antiphospholipid antibodies; cardiosurgery; heart valvulopathy; ischaemia;

D O I：

10.1191/0961203303lu445cr

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A patient with the antiphospholipid syndrome (APS), in whom a nonfatal myocardial infarction ensued after valvular heart replacement despite anticoagulation, is described. The report further stresses the role of concomitant risk co-factors in inducing thrombotic events and points out that cardiosurgery might represent a potential major risk for myocardial ischaemic damage in APS.

引用

页码：851 / 853

页数：3

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