The two hit hypothesis in the antiphospholipid syndrome: acute ischaemic heart involvement after valvular replacement despite anticoagulation in a patient with secondary APS

被引:22
作者
Bordin, G
Boldorini, R
Meroni, PL
机构
[1] Presidio Osped Bassini, Azienda Osped S Gerardo, Dept Internal Med, Milan, Italy
[2] Osped Maggiore La Carita, Pathol Serv, Novara, Italy
[3] Univ Milan, Dept Internal Med, Allergy & Clin Immunol Unit, Milan, Italy
关键词
antiphospholipid antibodies; cardiosurgery; heart valvulopathy; ischaemia;
D O I
10.1191/0961203303lu445cr
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A patient with the antiphospholipid syndrome (APS), in whom a nonfatal myocardial infarction ensued after valvular heart replacement despite anticoagulation, is described. The report further stresses the role of concomitant risk co-factors in inducing thrombotic events and points out that cardiosurgery might represent a potential major risk for myocardial ischaemic damage in APS.
引用
收藏
页码:851 / 853
页数:3
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