Carbon Nanotubes as Optical Sensors in Biomedicine

被引：111

作者：

Farrera, Consol ^{[1
,2
,3
]}

Andon, Fernando Torres ^{[4
,5
]}

Feliu, Neus ^{[6
,7
]}

机构：

[1] Kings Coll London, St Johns Inst Dermatol, London SE1 9RT, England

[2] Guys & St Thomas NHS Fdn Trust, NIHR Biomed Res Ctr, London SE1 9RT, England

[3] Kings Coll London, Guys Hosp, London SE1 9RT, England

[4] IRCCS Humanitas Clin & Res Inst, Lab Cellular Immunol, I-20089 Rozzano Milano, Italy

[5] Univ Santiago de Compostela, Ctr Res Mol Med & Chron Dis CIMUS, Santiago De Compostela 15706, Spain

[6] Karolinska Inst, Dept Lab Med, Expt Canc Med, S-14186 Stockholm, Sweden

[7] Univ Hamburg, Ctr Hybrid Nanostruct CHyN, Fac Phys, D-20146 Hamburg, Germany

来源：

ACS NANO | 2017年 / 11卷 / 11期

关键词：

NEAR-INFRARED WINDOW; COLLOIDAL NANOPARTICLES; MOLECULAR RECOGNITION; PHOTOLUMINESCENCE; NANOMATERIALS; BIODEGRADATION; FLUORESCENCE; REVEALS; CELLS; DNA;

D O I：

10.1021/acsnano.7b06701

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Single-walled carbon nanotubes (SWCNTs) have become potential candidates for a wide range of medical applications including sensing, imaging, and drug delivery. Their photophysical properties (i.e., the capacity to emit in the near-infrared), excellent photostability, and fluorescence, which is highly sensitive to the local environment, make SWCNTs promising optical probes in biomedicine. In this Perspective, we discuss the existing strategies for and challenges of using carbon nanotubes for medical diagnosis based on intracellular sensing as well as discuss also their biocompatibility and degradability. Finally, we highlight the potential improvements of this nano technology and future directions in the field of carbon nanotubes for biomedical applications.

引用

页码：10637 / 10643

页数：7

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