Antiinflammatory effect of petroleum ether extract of leaves of Litchi chinensis Gaertn (Sapindaceae)

被引：64

作者：

Besra, SE ^{[1
]}

Sharma, RM ^{[1
]}

Gomes, A ^{[1
]}

机构：

[1] INDIAN INST CHEM BIOL,NEW DRUG DEV DIV,CALCUTTA 700032,W BENGAL,INDIA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1996年 / 54卷 / 01期

关键词：

Litchi chinensis leaves; antiinflammatory; analgesic; anti-pyretic;

D O I：

10.1016/0378-8741(96)01440-7

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Pharmacological studies were conducted with the petroleum ether extract of leaves of the plant Litchi chinensis Gaertn. (Sapindaceae) on experimental animals. The extract was found to possess antiinflammatory, analgesic and antipyretic activity. Acute toxicity studies revealed that the extract, up to a dose of 1 g/kg intraperitoneally, was nontoxic. The extract did not inhibit arachidonic acid-induced paw inflammation thus indicating that it may inhibit the cyclooxygenase pathway of arachidonic acid metabolism. The extract also enhanced peritoneal cell exudate along with macrophage significantly.

引用

页码：1 / 6

页数：6

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