Electrophilic aromatic fluorination with fluorine:: meta-Directed fluorination of anilines

被引：7
作者：
Alric, JP [1 ]
Marquet, B [1 ]
Billard, T [1 ]
Langlois, BR [1 ]
机构：
[1] Univ Lyon 1, CNRS, UMR 5181, Lab SERCOF, F-69622 Villeurbanne, France
来源：
JOURNAL OF FLUORINE CHEMISTRY | 2005年 / 126卷 / 04期
关键词：
anilines; fluorine; fluoroanilines; triflic acid; fluorination;
D O I：
10.1016/j.jfluchem.2005.02.013
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Anilines are mainly or selectively fluorinated in the meta-position with F, when dissolved in triflic acid, sometimes in the presence of small quantities of antimony pentafluoride. The regioselectivity is increased when an electron-donating substituent is present at the para-position. (c) 2005 Elsevier B.V. All rights reserved.
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页码：661 / 667
页数：7
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