The tripartite motif family identifies cell compartments

被引：1176

作者：

Reymond, A

Meroni, G

Fantozzi, A

Merla, G

Cairo, S

Luzi, L

Riganelli, D

Zanaria, E

Messali, S

Cainarca, S

Guffanti, A

Minucci, S

Pelicci, PG

Ballabio, A

机构：

[1] TIGEM, Milan, Italy

[2] Univ Perugia, Internal Med & Oncol Sci Inst, I-06100 Perugia, Italy

[3] European Inst Oncol, Dept Expt Oncol, I-20141 Milan, Italy

[4] Uiv Vita & Salute, Milan, Italy

来源：

EMBO JOURNAL | 2001年 / 20卷 / 09期

关键词：

cell compartmentalization; functional genomics; nuclear bodies; RBCC; tripartite motif;

D O I：

10.1093/emboj/20.9.2140

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM), A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.

引用

页码：2140 / 2151

页数：12

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