Skin anti-inflammatory activity of water-soluble fullerene nanocomposites encompassed by sodium hyaluronate

被引：3

作者：

Wang, Tao ^{[1
]}

Li, Hui ^{[2
]}

Xu, Zhe ^{[2
]}

Wang, Chunru ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Mol Nanostruct & Nanotechnol, Beijing 100190, Peoples R China

[2] Beijing FULLCAN Biotechnol Co Ltd, Beijing, Peoples R China

来源：

JOURNAL OF COSMETIC DERMATOLOGY | 2022年 / 21卷 / 09期

基金：

中国博士后科学基金;

关键词：

fullerene; nanocomposites; skin anti-inflammatory; sodium hyaluronate;

D O I：

10.1111/jocd.14711

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Fullerene is one of the nanomaterials that has a value in dermatological and cosmetic applications. In present work, we designed and prepared water-soluble nano-scale C60 encompassed by sodium hyaluronate. The rat ear swelling test was utilized to evaluate the anti-inflammatory activity of encompassed C60. The measurement shows that the rat ear swelling rate of C60 administrated group is reduced to less than 10%, which shows good anti-inflammatory activity. Its anti-inflammatory activity is roughly calculated as 10 times than that of dipotassium glycyrrhizinate and five times than that of tanshinone. In conclusion, the fullerenes encapsulated by sodium hyaluronate have great potential in skin care and auxiliary treatment of dermatosis.

引用

页码：4016 / 4019

页数：4