Magnetic resonance elastography of the brain

被引：316

作者：

Kruse, Scott A. ^{[1
]}

Rose, Gregory H. ^{[1
]}

Glaser, Kevin J. ^{[1
]}

Manduca, Armando ^{[1
]}

Felmlee, Joel P. ^{[1
]}

Jack, Clifford R., Jr. ^{[1
]}

Ehman, Richard L. ^{[1
]}

机构：

[1] Mayo Clin, Dept Radiol, Rochester, MN 55905 USA

来源：

NEUROIMAGE | 2008年 / 39卷 / 01期

关键词：

magnetic resonance elastography; shear stiffness; elasticity; mechanical properties; tissue characterization; brain;

D O I：

10.1016/j.neuroimage.2007.08.030

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The purpose of this study was to obtain normative data using magnetic resonance elastography (MRE) (a) to obtain estimates of the shear modulus of human cerebral tissue in vivo and (b) to assess a possible age dependence of the shear modulus of cerebral tissue in healthy adult volunteers. MR elastography studies were performed on tissue-simulating gelatin phantoms and 25 healthy adult volunteers. The data were analyzed using spatiotemporal filters and a local frequency estimating algorithm. Statistical analysis was performed using a paired t-test. The mean shear stiffness of cerebral white matter was 13.6 kPa (95% Cl 12.3 to 14.8 kPa); while that of gray matter was lower at 5.22 kPa (95% Cl 4.76 to 5.66 kPa). The difference was statistically significant (p < 0.0001). (C) 2007 Published by Elsevier Inc.

引用

页码：231 / 237

页数：7

共 64 条

[1] Material characterization of the brainstem from oscillatory shear tests [J].