Dipeptide-functionalized MIL-101(Fe) as efficient material for ibuprofen delivery

被引：12
作者：
Asadi, Fatemeh Rajab [1 ]
Hamzavi, Seyedeh Fazileh [2 ]
Shahverdizadeh, Gholam Hossein [3 ]
Ilkhchi, Mahdi Ghasedi [3 ]
Hosseinzadeh-Khanmiri, Rahim [3 ]
机构：
[1] Shahid Beheshti Univ, Dept Phys, Tehran, Iran
[2] Islamic Azad Univ, Sci & Res Branch, Dept Marine Biol, Tehran, Iran
[3] Islamic Azad Univ, Tabriz Branch, Dept Chem, Tabriz, Iran
来源：
APPLIED ORGANOMETALLIC CHEMISTRY | 2018年 / 32卷 / 12期
关键词：
characterization; dipeptide; functionalization; ibuprofen delivery; MIL-101(Fe); METAL-ORGANIC-FRAMEWORK; DRUG-DELIVERY; MESOPOROUS SILICA; NANOPARTICLES; ADSORPTION; MOF; COMPOSITES; CATALYST; RELEASE; CARBON;
D O I：
10.1002/aoc.4552
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two derivatives of a dipeptide-functionalized metal-organic framework were synthesized through isocyanide-based multi-component reactions from amine-containing MIL-101(Fe). The functionalized materials were characterized by means of Fourier transform infrared spectroscopy, X-ray diffraction Brunauer-Emmett-Teller measurements, thermogravimetric analysis, elemental analysis and scanning electron microscopy. The performances of these functionalized MIL-101(Fe) materials with different functions were evaluated for ibuprofen delivery during six days, showing a good ability for adsorption of significant content of the drug and very slow release.
引用
收藏
页数：6
相关论文
共 36 条
[11]   Hydrogels in drug delivery: Progress and challenges [J].
Hoare, Todd R. ;
Kohane, Daniel S. .
POLYMER, 2008, 49 (08) :1993-2007
[12]  
Horcajada P., 2006, ANGEW CHEM, V118, P6120, DOI [DOI 10.1002/ANGE.200601878, 10.1002/ange.200601878]
[13]  
Horcajada P, 2010, NAT MATER, V9, P172, DOI [10.1038/NMAT2608, 10.1038/nmat2608, 10.1038/NMAT260B]
[14]   Magnetic Fe3O4@mesoporous silica composites for drug delivery and bioadsorption [J].
Huang, Shanshan ;
Li, Chunxia ;
Cheng, Ziyong ;
Fan, Yong ;
Yang, Piaoping ;
Zhang, Cuimiao ;
Yang, Kuiyue ;
Lin, Jun .
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2012, 376 :312-321
[15]   Metal-organic frameworks as potential drug carriers [J].
Huxford, Rachel C. ;
Della Rocca, Joseph ;
Lin, Wenbin .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2010, 14 (02) :262-268
[16]   Synthesis and characterization of fluconazole-functionalized magnetic nanoparticles as a catalyst for the synthesis of 3-aryl and 3-amino-imidazo[1,2-a]pyridines [J].
Jafarzadeh, Mohammad ;
Soleimani, Ebrahim ;
Sepahvand, Heshmatollah ;
Adnan, Rohana .
RSC ADVANCES, 2015, 5 (53) :42744-42753
[17]   Hollow Mesoporous Silica@Metal-Organic Framework and Applications for pH-Responsive Drug Delivery [J].
Jia, Xiaomin ;
Yang, Zhiyuan ;
Wang, Yujun ;
Chen, Ya ;
Yuan, Haitao ;
Chen, Heyin ;
Xu, Xiaoxiang ;
Gao, Xueqing ;
Liang, Zuozhong ;
Sun, Yu ;
Li, Jian-Rong ;
Zheng, Haoquan ;
Cao, Rui .
CHEMMEDCHEM, 2018, 13 (05) :400-405
[18]   Synthesis and characterization of Co3O4 immobilized on dipeptide-functionalized silica-coated magnetite nanoparticles as a catalyst for the selective aerobic oxidation of alcohols [J].
Khodaei, Mohammad Mehdi ;
Dehghan, Mahsa .
NEW JOURNAL OF CHEMISTRY, 2018, 42 (14) :11381-11389
[19]   Structurally Ordered Mesoporous Carbon Nanoparticles as Transmembrane Delivery Vehicle in Human Cancer Cells [J].
Kim, Tae-Wan ;
Chung, Po-Wen ;
Slowing, Igor I. ;
Tsunoda, Makoto ;
Yeung, Edward S. ;
Lin, Victor S. -Y. .
NANO LETTERS, 2008, 8 (11) :3724-3727
[20]  
Lee V., 1990, PEPTIDE PROTEIN DRUG, V4
1234