CNS Response to Osimertinib in Patients with T790M-Positive Advanced NSCLC: Pooled Data from Two Phase II Trials

被引：20

作者：

Goss, Glenwood ^{[1
]}

Tsai, Chun -Ming ^{[2
,3
]}

Shepherd, Frances ^{[4
]}

Ahn, Myung-Ju ^{[5
]}

Bazhenova, Lyudmila ^{[6
]}

Crino, Lucio ^{[7
]}

De Marinis, Filippo ^{[8
]}

Felip, Enriqueta ^{[9
]}

Morabito, Alessandro ^{[10
]}

Hodge, Rachel ^{[11
]}

Cantarini, Mireille ^{[12
]}

Mitsudomi, Tetsuya ^{[13
]}

Janne, Pasi ^{[14
]}

Yang, James Chih-Hsin ^{[15
]}

机构：

[1] Univ Ottawa, Ottawa Hosp, Ctr Canc, Med Oncol, Ottawa, ON, Canada

[2] Natl Yang Ming Univ, Taipei Vet Gen Hosp, Taipei, Taiwan

[3] Natl Yang Ming Univ, Sch Med, Taipei, Taiwan

[4] Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada

[5] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Med, Seoul, South Korea

[6] Uc San Diego Hlth, Moores Canc Ctr, San Diego, CA USA

[7] Azienda Osped Perugia, Santa Maria Della Misericordia Hosp, Perugia, Italy

[8] European Inst Oncol, Thorac Oncol Div, Milan, Italy

[9] Vall DHebron Inst Oncol, Barcelona, Spain

[10] Inst Nazl Tumori Napoli, Naples, Italy

[11] Astrazeneca, Cambridge, England

[12] Astrazeneca, Macclesfield, Cheshire, England

[13] Kindai Univ, Fac Med, Thorac Surg, Osaka, Japan

[14] Dana Farber Canc Inst, Lowe Ctr Thorac Oncol, Boston, MA 02115 USA

[15] Natl Taiwan Univ, Canc Res Ctr, Taipei, Taiwan

来源：

关键词：

brain metastases; AZD9291; osimertinib; T790M;

D O I：

10.1016/j.jtho.2016.11.514

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

MA16.11

引用

页码：S440 / S441

页数：2