Dispersion due to wall interactions in microfluidic separation systems

被引：33

作者：

Datta, Subhra ^{[1
]}

Ghosal, Sandip ^{[1
]}

机构：

[1] Northwestern Univ, Dept Mech Engn, Evanston, IL 60208 USA

来源：

PHYSICS OF FLUIDS | 2008年 / 20卷 / 01期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1063/1.2828098

中图分类号：

O3 [力学];

学科分类号：

08 ; 0801 ;

摘要：

The transport of a solute in a straight microchannel of axially variable cross-sectional shape in the presence of an inhomogeneous flow field and an adsorption-desorption process on the wall is studied, motivated by applications to capillary electrophoresis and open-channel capillary electrochromatography. An asymptotic approach based on the long time limit is adopted that reduces the problem to the solution of a one-dimensional transport equation. The reduced model is integrated numerically to study the effects of inhomogeneous electro-osmotic flow and adsorption-desorption kinetics on solute migration and dispersion in a rectangular microchannel. The accuracy of the asymptotic equations is checked by the direct numerical solution of the original three-dimensional transport problem. (C) 2008 American Institute of Physics.

引用

页数：14

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