A randomized prospective study of microdose leuprolide versus ganirelix in in vitro fertilization cycles for poor responders

被引:71
作者
Schmidt, DW [1 ]
Bremner, T [1 ]
Orris, JJ [1 ]
Maier, DB [1 ]
Benadiva, CA [1 ]
Nulsen, JC [1 ]
机构
[1] Univ Connecticut, Ctr Hlth, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil,Ctr Adv Reprod S, Farmington, CT 06030 USA
关键词
D O I
10.1016/j.fertnstert.2004.10.053
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Forty-eight patients who met the criteria of poor response during prior gonadotropin stimulation were enrolled in a randomized prospective study comparing a gonadotropin-releasing hormone (GnRH) antagonist protocol, using ganirelix acetate, with a microdose GnRH agonist protocol for in vitro fertilization-embryo transfer (IVF-ET). This pilot study contributes to the literature of poor response IVF treatment protocols because the use of ganirelix appears to be as effective as the microdose protocol and may be a superior choice in terms of cost and convenience for the patient. (Fertil Steril (R) 2005;83:1568-71. (c) 2005 by American Society for Reproductive Medicine.)
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页码:1568 / 1571
页数:4
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