Synthesis, Characterization and Antimicrobial Screening of Various Ferrocenyl Schiff Bases against Gram-positive and Gram-negative Bacteria

被引：0
作者：
Olatunde, Oladeji S. [1 ]
Monisola, Ikhile I. [1 ]
Messai, Mamo [1 ]
Patrick, Ndungu G. [1 ]
Derek, Ndinteh T. [1 ]
机构：
[1] Univ Johannesburg, Fac Sci, Dept Chem Sci, Johannesburg, South Africa
来源：
CHINESE JOURNAL OF INORGANIC CHEMISTRY | 2022年 / 38卷 / 04期
关键词：
antibacterial; Schiff bases; nalidixic; synthesis; inhibition; COMPLEXES; LIGANDS; ANTIFUNGAL; RHODIUM(I); CHEMISTRY; CATALYST;
D O I：
10.11862/CJIC.2022.065
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Ten ferrocenyl Schiff bases 1-10 were synthesized and characterized using UV-Vis spectroscopy, FT. IR, elemental analysis, H-1 and C-13 NMR spectroscopy. The synthesized compounds were evaluated against 11 bacteria strains (Bacillus subtilis ATCC19659, Klebsiella aerogenes ATCC13882, Enterococcus faecalis ATCC13047, Myco. bacterium smegmatis MC2155, Staphylococcus epidermidis ATCC14990, Staphylococcus aureus ATCC25923, Esche. richia coli ATCC25922, Enterobacter cloacae ATCC13047, Klebsiella oxytoca ATCC8724, Proteus mirabilis ATCC7002, Proteus vulgaris ATCC6380). The results obtained from antibacterial assay indicated that the synthe. sized Schiff bases 1. 10 inhibited potential growth of Klebsiella aerogenes with the minimum inhibitory concentration (MIC) ranging from 15.6 to 31.25 mu g.mL(-1) and Enterococcus faecalis with MIC the range between 31.25 and 125 mu g.mL(-1) in comparison with the standard nalidixic acid and streptomycin sulfate.
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页码：705 / 715
页数：11
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