Supportive Care Needs and the Impact of Loss of Functioning and Symptom Burden on the Quality of Life in Patients with Advanced Colorectal Cancer

被引：5

作者：

Miniotti, Marco ^{[1
]}

Bassino, Stefania ^{[1
]}

Fanchini, Laura ^{[2
]}

Ritorto, Giuliana ^{[2
]}

Leombruni, Paolo ^{[1
]}

机构：

[1] Univ Turin, Rita Levi Montalcini Dept Neurosci, Clin Psychol Unit, Turin, Italy

[2] Citta Salute & Sci Torino Univ Hosp, Oncol Dept, ColoRectal Canc Unit, Turin, Italy

来源：

ONCOLOGY RESEARCH AND TREATMENT | 2022年 / 45卷 / 05期

关键词：

Supportive care needs; Quality of life; Symptom burden; Colorectal cancer; Multiple mediation; UNMET NEEDS; SURVIVORS; STATISTICS;

D O I：

10.1159/000521753

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background/Aims: Relationships between loss of functioning, symptom burden, supportive care needs, and quality of life (QoL) have been suggested in cancer populations. This cross-sectional study further investigates these relationships through mediation analyses. Methods: A total of 276 advanced colorectal cancer (CRC) patients completed validated instruments to assess cancer-related functioning, symptoms, supportive care needs, and QoL. Pearson's correlations and multiple mediation models with bootstrapping method were performed. Results: QoL had negative correlations with supportive care needs, positive correlations with functioning measures, and negative correlations with symptom scales. Supportive care needs had negative correlations with functioning measures and positive correlations with symptom scales. Mediation analyses showed significant indirect effects of CRC-related functioning and symptoms on QoL through supportive care needs. Conclusions: Significant links between CRC-related loss of functioning, symptom burden, QoL, and supportive care needs have been established. Longitudinal studies are planned to clarify cause-andeffects relationships and establish sequences of events. (C) 2022 S. Karger AG, Basel

引用

页码：262 / 270

页数：9

共 30 条

[1] Impact of emotional competence on supportive care needs, anxiety and depression symptoms of cancer patients: a multiple mediation model
Baudry, A. -S.
Lelorain, S.
Mahieuxe, M.
Christophe, V.
[J]. SUPPORTIVE CARE IN CANCER, 2018, 26 (01) : 223 - 230
[2] Changes in supportive care needs after first-line treatment for ovarian cancer: identifying care priorities and risk factors for future unmet needs
Beesley, Vanessa L.
Price, Melanie A.
Webb, Penelope M.
O'Rourke, Peter
Marquart, Louise
Butow, Phyllis N.
[J]. PSYCHO-ONCOLOGY, 2013, 22 (07) : 1565 - 1571
[3] Bonevski B, 2000, CANCER, V88, P217, DOI 10.1002/(SICI)1097-0142(20000101)88:1<217::AID-CNCR29>3.0.CO
[4] 2-Y
[5] Prevalence and correlates of cancer survivors' supportive care needs 6 months after diagnosis: a population-based cross-sectional study
Boyes, Allison W.
Girgis, Afaf
D'Este, Catherine
Zucca, Alison C.
[J]. BMC CANCER, 2012, 12
[6] Identifying trajectory clusters in breast cancer survivors' supportive care needs, psychosocial difficulties, and resources from the completion of primary treatment to 8 months later
Bredart, A.
Merdy, O.
Sigal-Zafrani, B.
Fiszer, C.
Dolbeault, S.
Hardouin, J-B.
[J]. SUPPORTIVE CARE IN CANCER, 2016, 24 (01) : 357 - 366
[7] Unmet needs mediate the relationship between symptoms and quality of life in breast cancer survivors
Cheng, K. K. F.
Wong, W. H.
Koh, C.
[J]. SUPPORTIVE CARE IN CANCER, 2016, 24 (05) : 2025 - 2033
[8] Fayers P., 2001, EORTC QLQ C30 SCORIN, V3
[9] Cancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
Ferlay, J.
Steliarova-Foucher, E.
Lortet-Tieulent, J.
Rosso, S.
Coebergh, J. W. W.
Comber, H.
Forman, D.
Bray, F.
[J]. EUROPEAN JOURNAL OF CANCER, 2013, 49 (06) : 1374 - 1403
[10] IT'S NOT OVER WHEN IT'S OVER: LONG-TERM SYMPTOMS IN CANCER SURVIVORS-A SYSTEMATIC REVIEW
Harrington, Cherise B.
Hansen, Jennifer A.
Moskowitz, Michal
Todd, Briana L.
Feuerstein, Michael
[J]. INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE, 2010, 40 (02) : 163 - 181

← 1 2 3 →