Complications of multiple myeloma

被引：51

作者：

Blade, Joan ^{[1
]}

Rosinol, Laura ^{[1
]}

机构：

[1] Hosp Clin Barcelona, Inst Hematol & Oncol, Postgrad Sch Hematol Farreras Valenti, Inst Invest Biomed August Pi & Sunyer, Barcelona, Spain

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2007年 / 21卷 / 06期

关键词：

D O I：

10.1016/j.hoc.2007.08.006

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Multiple myeloma, also known as myeloma or plasma cell myeloma, is a progressive hematologic disease. Complications of multiple myeloma include renal insufficiency, hematologic complications (anemia, bone marrow failure, bleeding disorders), infections, bone complications (pathologic fractures, spinal cord compression, hyercalcemia), and neurologic complications (spinal cord and nerve root compression, intracranial plasmacytomas, leptomeningeal involvement, among others). This article reviews these various complications connected to multiple myeloma, examining their various causes and possible treatment.

引用

页码：1231 / +

页数：17

共 73 条

[21] A COMPARISON OF THE INCIDENCE OF THE MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID-LEUKEMIA FOLLOWING MELPHALAN AND CYCLOPHOSPHAMIDE TREATMENT FOR MYELOMATOSIS - A REPORT TO THE MEDICAL-RESEARCH-COUNCILS WORKING PARTY ON LEUKEMIA IN ADULTS [J].

CUZICK, J ;

ERSKINE, S ;

EDELMAN, D ;

GALTON, DAG .

BRITISH JOURNAL OF CANCER, 1987, 55 (05) :523-529

[22] Biology and therapy of immunoglobulin deposition diseases [J].

Dhodapkar, MV ;

Merlini, G ;

Solomon, A .

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 1997, 11 (01) :89-&

[23]

Durie BGM, 2005, NEW ENGL J MED, V353, P99

[24] Myeloma of the central nervous system: Strong association with unfavorable chromosomal abnormalities and other high-risk disease features [J].

Fassas, ABT ;

Ward, S ;

Muwalla, F ;

Van Hemert, R ;

Schluterman, K ;

Harik, S ;

Tricot, G .

LEUKEMIA & LYMPHOMA, 2004, 45 (02) :291-300

[25]

Gawler J, 2004, MYELOMA BIOL MANAGEM, P269

[26] Preceding standard therapy is the likely cause of MDS after autotransplants for multiple myeloma [J].

Govindarajan, R ;

Jagannath, S ;

Flick, JT ;

Vesole, DH ;

Sawyer, J ;

Barlogie, B ;

Tricot, G .

BRITISH JOURNAL OF HAEMATOLOGY, 1996, 95 (02) :349-353

[27] IMMUNOLOGICAL FACTORS AND RISK OF INFECTION IN PLATEAU-PHASE MYELOMA [J].

HARGREAVES, RM ;

LEA, JR ;

GRIFFITHS, H ;

FAUX, JA ;

HOLT, JM ;

REID, C ;

BUNCH, C ;

LEE, M ;

CHAPEL, HM .

JOURNAL OF CLINICAL PATHOLOGY, 1995, 48 (03) :260-266

[28]

Henson R, 1982, CANC NERVOUS SYSTEM

[29] RENAL LESIONS IN MULTIPLE-MYELOMA - THEIR RELATIONSHIP TO ASSOCIATED PROTEIN ABNORMALITIES [J].

HILL, GS ;

MORELMAROGER, L ;

MERY, JP ;

BROUET, JC ;

MIGNON, F .

AMERICAN JOURNAL OF KIDNEY DISEASES, 1983, 2 (04) :423-438

[30]

HOEN B, 1995, NEPHROL DIAL TRANSPL, V10, P377

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