Electrochemical sensors and biosensors for the determination of diclofenac in pharmaceutical, biological and water samples

被引：56

作者：

Boumya, Wafaa ^{[1
,2
]}

Taoufik, Nawal ^{[1
]}

Achak, Mounia ^{[2
,3
]}

Bessbousse, Haad ^{[4
]}

Elhalil, Alaaeddine ^{[5
]}

Barka, Noureddine ^{[1
]}

机构：

[1] Sultan Moulay Slimane Univ Beni Mellal, Res Grp Environm Sci & Appl Mat SEMA, FP Khouribga,BP 145, Khouribga 25000, Morocco

[2] Chouaib Doukkali Univ, Lab Sci Ingn Energie, Ecole Natl Sci Appl, El Jadida, Morocco

[3] Mohammed VI Polytech Univ, Chem & Biochem Sci Green Proc Engn CBS, Ben Guerir, Morocco

[4] Chouaib Doukkali Univ, Lab Management Agri Durable, EST Sidi Bennour, El Jadida, Morocco

[5] Univ Hassan 2, Lab Engn Proc & Environm LEPE, EST Casablanca, Casablanca, Morocco

来源：

TALANTA OPEN | 2021年 / 3卷

关键词：

Diclofenac; Electrochemical detection; Modified electrodes; Detection limit; Recovery;

D O I：

10.1016/j.talo.2020.100026

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Diclofenac is a non-steroidal anti-inflammatory drug of wide use around the world for the treatment of several diseases such as ankylosing spondylitis, acute muscle pain conditions, and osteoarthritis. Although in proper doses it does not display any side effects, an overdose of diclofenac can cause adverse effects in the human body. Moreover, the presence of diclofenac in ecosystems directly affects the health of living organisms, even if it is present at trace. Therefore, the development of analytical tools for diclofenac monitoring was needed. In this context, electrochemical sensing and biosensing methods have been commonly reported. In this review, a critical evaluation of the methods employed for diclofenac analysis is presented according to the following classifications: potentiometric sensors, sensing at non-modified solid electrodes, chemically modified electrodes and biosensors. Recent developments related to the use of electrochemical detection of diclofenac in pharmaceutical formulations, biological fluids and environmental samples were reported and discussed.

引用

页数：13

共 83 条

[1] Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium [J].