Convalescent Plasma for Outpatients with Covid-19

被引：2
作者：
Fisher, David [1 ]
Malnick, Stephen [1 ]
机构：
[1] Kaplan Med Ctr, Rehovot, Israel
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2021年
关键词：
THERAPY;
D O I：
10.1056/NEJMc2114591
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
To the Editor: In the Covid-19 Convalescent Plasma in Outpatients (C3PO) trial,(1) Korley et al., members of the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN), administered convalescent plasma to high-risk outpatients within 1 week after the onset of symptoms of Covid-19. It is unclear why the authors selected 1 week instead of a shorter time frame, since it has been shown that the 30-day and 60-day mortality benefits of convalescent plasma have been observed when it is administered within 3 days after diagnosis and that the benefit dissipates after this point.(2,3) The aim of their trial was to . . .
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