Phenotypical and genetic analysis of human immunodeficiency virus (HIV-1) and subtype B isolated in Russia

被引：0
作者：
Selimova, LM [1 ]
Bobkov, AF
Serebrovskaya, LV
Kravchenko, AV
Lyubaeva, YV
Kazennova, YV
Sankov, MN
Pokrovsky, VV
机构：
[1] DI Ivanovskii Virol Inst, Moscow 123098, Russia
[2] Russian Sci Educ AIDS Prevent Ctr, Moscow, Russia
来源：
VOPROSY VIRUSOLOGII | 1998年 / 43卷 / 03期
关键词：
type I human immunodeficiency virus; subtype B; isolate; phenotype; genotype; characteristics;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Human immunodeficiency type 1 virus env subtype B 95RU25B isolated from a Russian citizen is studied. The time course of clinical changes and immunological parameters over 5.5 years is presented. Phenotypical characteristics of the isolate were assessed by culturing in different sensitive cell cultures. Genotyping by the heteroduplex analysis and env gene sequencing were carried out. 95RU25B variant is capable of infecting a wide spectrum of cell cultures and by the type of replication can be classified with the S/L.3 group. The phenotypical properties of the isolate apparently determine the characteristic features in the primary structure of V3 loop.
引用
收藏
页码：110 / 113
页数：4
相关论文
共 18 条
  • [1] ISOLATION OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) FROM PLASMA DURING PRIMARY HIV-INFECTION
    ALBERT, J
    GAINES, H
    SONNERBORG, A
    NYSTROM, G
    PEHRSON, PO
    CHIODI, F
    VONSYDOW, M
    MOBERG, L
    LIDMAN, K
    CHRISTENSSON, B
    ASJO, B
    FENYO, EM
    [J]. JOURNAL OF MEDICAL VIROLOGY, 1987, 23 (01) : 67 - 73
  • [2] Genetic heterogeneity of HIV type 1 in Russia: Identification of H variants and relationship with epidemiological data
    Bobkov, A
    CheingsongPopov, R
    Selimova, L
    Kazennova, E
    Karasyova, N
    Kravchenko, A
    Ladnaya, N
    Pokrovsky, V
    Weber, J
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 1996, 12 (18) : 1687 - 1690
  • [3] HIV type 1 subtype E in Russia
    Bobkov, A
    CheingsongPopov, R
    Selimova, L
    Ladnaya, N
    Kazennova, E
    Kravchenko, A
    Pokrovsky, V
    Weber, J
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 1997, 13 (08) : 725 - 727
  • [4] BOBKOV AF, 1997, VOP VIRUSOL+, P13
  • [5] Mapping of independent V3 envelope determinants of human immunodeficiency virus type 1 macrophage tropism and syncytium formation in lymphocytes
    Chesebro, B
    Wehrly, K
    Nishio, J
    Perryman, S
    [J]. JOURNAL OF VIROLOGY, 1996, 70 (12) : 9055 - 9059
  • [6] GENETIC-RELATIONSHIPS DETERMINED BY A DNA HETERODUPLEX MOBILITY ASSAY - ANALYSIS OF HIV-1 ENV GENES
    DELWART, EL
    SHPAER, EG
    LOUWAGIE, J
    MCCUTCHAN, FE
    GREZ, M
    RUBSAMENWAIGMANN, H
    MULLINS, JI
    [J]. SCIENCE, 1993, 262 (5137) : 1257 - 1261
  • [7] SYNCYTIUM-INDUCING AND NON-SYNCYTIUM-INDUCING CAPACITY OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 SUBTYPES OTHER THAN B - PHENOTYPIC AND GENOTYPIC CHARACTERISTICS
    DEWOLF, F
    HOGERVORST, E
    GOUDSMIT, J
    FENYO, EM
    RUBSAMENWAIGMANN, H
    HOLMES, H
    GALVAOCASTRO, B
    KARITA, E
    WASI, C
    SEMPALA, SDK
    BAAN, E
    ZORGDRAGER, F
    LUKASHOV, V
    OSMANOV, S
    KUIKEN, C
    CORNELISSEN, M
    BELSEY, EM
    HEYWARD, W
    ESPARZA, J
    VANDEPERRE, P
    SEMPALA, S
    TUGUME, B
    BIRYAHWAHO, B
    VONBRIESEN, H
    ESSER, R
    GREZ, M
    NEWBERRY, A
    RANJBAR, S
    TOMLINSON, P
    BRADAC, J
    MCCUTCHAN, F
    LOUWAGIE, J
    HEGERICH, P
    LOPEZGALINDEZ, C
    OLIVARES, I
    DOPAZO, J
    MULLINS, JI
    DELWART, EL
    BACHMANN, HM
    HAHN, BH
    GAO, F
    YUE, L
    SARAGOSTI, S
    SCHOCHETMAN, G
    KALISH, M
    LUO, CC
    GEORGE, R
    PAU, CP
    WEBER, J
    CHEINGSONGPOPOV, R
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 1994, 10 (11) : 1387 - 1400
  • [8] PHENOTYPE-ASSOCIATED SEQUENCE VARIATION IN THE 3RD VARIABLE DOMAIN OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 GP120 MOLECULE
    FOUCHIER, RAM
    GROENINK, M
    KOOTSTRA, NA
    TERSMETTE, M
    HUISMAN, HG
    MIEDEMA, F
    SCHUITEMAKER, H
    [J]. JOURNAL OF VIROLOGY, 1992, 66 (05) : 3183 - 3187
  • [9] The emerging genetic diversity of HIV - The importance of global surveillance for diagnostics, research, and prevention
    Hu, DJ
    Dondero, TJ
    Rayfield, MA
    George, JR
    Schochetman, G
    Jaffe, HW
    Luo, CC
    Kalish, ML
    Weniger, BG
    Pau, CP
    Schable, CA
    Curran, JW
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 275 (03): : 210 - 216
  • [10] IDENTIFICATION OF THE ENVELOPE V3 LOOP AS THE PRIMARY DETERMINANT OF CELL TROPISM IN HIV-1
    HWANG, SS
    BOYLE, TJ
    LYERLY, HK
    CULLEN, BR
    [J]. SCIENCE, 1991, 253 (5015) : 71 - 74
12